FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Hr39Δ48
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General Information
Symbol
Dmel\Hr39Δ48
Species
D. melanogaster
Name
FlyBase ID
FBal0363152
Feature type
allele
Associated gene
Dmel\Hr39
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Praggastis et al., 2021, Thummel, 2020.10.13)
Progenitor genotype
Cytology
Description

2bp deletion in the first protein-coding exon of Hr39, resulting in a frameshift and premature stop codon. Predicted to affect all Hr39 isoforms.

(Praggastis et al., 2021)

Intragenic deletion affecting all Hr39 isoforms.

(Thummel, 2020.10.13)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2L:21,254,924..21,254,925 [+]
Comment:

A 2bp deletion in the first protein-coding exon of Hr39, resulting in a frameshift and premature translation termination.

(Praggastis et al., 2021)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Control females mated to Hr39Δ3/Hr39Δ3 males lay fewer eggs than when mated to control males.

      (Praggastis et al., 2021)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescued by

      Hr39Δ3/Hr39Δ48 is partially rescued by Scer\GAL4prd.RG1/Hr39UAS.ORF.GW.Tag:HA

      (Praggastis et al., 2021)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      HR39Δ48
      (Praggastis et al., 2021)
      Hr39Delta48
      (Thummel, 2020.10.13)
      Hr39Δ48
      Name Synonyms
      Secondary FlyBase IDs
        References (2)