FlyBase Allele Report: Dmel\Tgs1[2-3]

FB2026_02 , released June 18, 2026

FB2026_02 , released June 18, 2026

Allele: Dmel\Tgs1^2-3

General Information

Symbol

Dmel\Tgs1^2-3

Species

D. melanogaster

Name

FlyBase ID

FBal0364097

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

amorphic allele - genetic evidence

Mutagen

Nature of the Allele

Allele class

amorphic allele - genetic evidence

(Cheng et al., 2020)

Mutagen

(Cheng et al., 2020)

gene targeting by homologous recombination

(Cheng et al., 2020)

Progenitor genotype

Cytology

Description

10bp deletion within the Tgs1 open reading frame; results in a frame-shift.

(Cheng et al., 2020)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die before end of second instar larval stage (with Df(3R)Exel6178)

(Cheng et al., 2020)

lethal - all die before end of second instar larval stage (with Tgs1^1-3)

(Cheng et al., 2020)

lethal - all die before end of second instar larval stage | recessive

(Cheng et al., 2020)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Tgs1^2-3/Tgs1^1-3 has increased mortality during development phenotype, suppressible by moi^t4.Tgs1-GFP

(Cheng et al., 2020)

Tgs1^2-3 has increased mortality during development phenotype, suppressible by moi^t4.G45R

(Cheng et al., 2020)

Tgs1^2-3 has increased mortality during development phenotype, suppressible by moi^t4.Tgs1-GFP

(Cheng et al., 2020)

Tgs1^2-3/Df(3R)Exel6178 has increased mortality during development phenotype, suppressible by moi^t4.Tgs1-GFP

(Cheng et al., 2020)

Other

Statement

Reference

Tgs1^2-3, Tgs1^t4.moi-G45R, moi^t4.G45R has male fertile phenotype

(Cheng et al., 2020)

Tgs1^2-3, Tgs1^GFP, moi^t4.Tgs1-GFP has male fertile phenotype

(Cheng et al., 2020)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Tgs1^2-3/Tgs1^1-3 is rescued by Tgs1^GFP

(Cheng et al., 2020)

Tgs1^2-3 is rescued by Tgs1^GFP

(Cheng et al., 2020)

Tgs1^2-3 is rescued by Tgs1^t4.moi-G45R

(Cheng et al., 2020)

Tgs1^2-3/Df(3R)Exel6178 is rescued by Tgs1^GFP

(Cheng et al., 2020)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Tgs1^2-3

tgs1^2-3

(Cheng et al., 2020)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections