FB2026_02 , released June 18, 2026
Allele: Dmel\Pect29
Open Close
General Information
Symbol
Dmel\Pect29
Species
D. melanogaster
Name
FlyBase ID
FBal0364837
Feature type
allele
Associated gene
Dmel\Pect
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Zhao and Wang, 2020)
Mutagen
ethyl methanesulfonate
(Zhao and Wang, 2020)
Progenitor genotype
Cytology
Description

Single nucleotide change in the conserved enzymatic domain (W>stop).

(Zhao and Wang, 2020)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:13,208,275..13,208,275 [+]
Nucleotide change:

G13208275A

Amino acid change:

W83term | Pect-PB; W83term | Pect-PC; W83term | Pect-PD; W83term | Pect-PE

Reported amino acid change:

W83term

Comment:

G to A nucleotide change at the second or third position of the Trp codon leads to a nonsense mutation (exact site of mutation unspecified). Site of nucleotide substitution in mutant inferred by FlyBase curator based on reported amino acid change.

(Zhao and Wang, 2020)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Electroretinogram (ERG) of adults containing eye-specific clones of Pect29 (in combination with Scer\FLP1[ey.PU]) exhibit persistence of light-evoked photoreceptor potential after the 20-s light stimulation and diminished ERG transients.

      Adults containing eye-specific clones of Pect29 (in combination with Scer\FLP1[ey.PU]) exhibit gradual loss of photoreceptor cells and rhabdomeres when flies are reared in a constant dark or a light/dark cycle.

      Adults containing eye-specific clones of Pect29 (in combination with Scer\FLP1[ey.PU]) exhibit disrupted synaptic vesicles in the lamina cartridge.

      (Zhao and Wang, 2020)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      NOT Enhanced by
      Suppressed by
      NOT suppressed by
      Statement
      Reference

      Pect29, Scer\FLP1ey.PU has abnormal neurophysiology | somatic clone phenotype, non-suppressible by rdgAGMR.PZ

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has abnormal neurophysiology | somatic clone phenotype, non-suppressible by laza1

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has decreased cell number | somatic clone | progressive phenotype, non-suppressible by Pcyt1GMR.PZ

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has decreased cell number | somatic clone | progressive phenotype, non-suppressible by PisdGMR.PZ/MarfHMC03883/Scer\GAL4GMR.long

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has decreased cell number | somatic clone | progressive phenotype, non-suppressible by PisdGMR.PZ/SERCAHMS02878/Scer\GAL4GMR.long

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has decreased cell number | somatic clone | progressive phenotype, non-suppressible by rdgAGMR.PZ

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has decreased cell number | somatic clone | progressive phenotype, non-suppressible by laza1

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has decreased cell number | somatic clone | progressive phenotype, non-suppressible by norpAP24

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has decreased cell number | somatic clone | progressive phenotype, non-suppressible by Scer\GAL4GMR.long/PisJF03315

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has decreased cell number | somatic clone | progressive phenotype, non-suppressible by Df(1)inaF-P106x

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has decreased cell number | somatic clone | progressive phenotype, non-suppressible by trp9

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has decreased cell number | somatic clone | progressive phenotype, non-suppressible by Pcyt1[+]/Pcyt1179

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has decreased cell number | somatic clone | progressive phenotype, non-suppressible by bbcGMR.PZ

      (Zhao and Wang, 2020)
      Phenotype Manifest In
      Enhanced by
      NOT Enhanced by
      Statement
      Reference

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, non-enhanceable by norpAP24

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, non-enhanceable by trp9

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, non-enhanceable by trp9

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, non-enhanceable by Pcyt1[+]/Pcyt1179

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, non-enhanceable by Pcyt1[+]/Pcyt1179

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, non-enhanceable by bbcGMR.PZ

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, non-enhanceable by bbcGMR.PZ

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, non-enhanceable by Pcyt1GMR.PZ

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, non-enhanceable by norpAP24

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, non-enhanceable by Pcyt1GMR.PZ

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, non-enhanceable by PisdGMR.PZ/MarfHMC03883/Scer\GAL4GMR.long

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, non-enhanceable by PisdGMR.PZ/MarfHMC03883/Scer\GAL4GMR.long

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, non-enhanceable by PisdGMR.PZ/SERCAHMS02878/Scer\GAL4GMR.long

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, non-enhanceable by PisdGMR.PZ/SERCAHMS02878/Scer\GAL4GMR.long

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, non-enhanceable by Scer\GAL4GMR.long/PisJF03315

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, non-enhanceable by Scer\GAL4GMR.long/PisJF03315

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, non-enhanceable by Df(1)inaF-P106x

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, non-enhanceable by Df(1)inaF-P106x

      (Zhao and Wang, 2020)
      Suppressed by
      Statement
      Reference

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, suppressible by PisdGMR.PZ

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, suppressible by PisdGMR.PZ

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has retina | somatic clone phenotype, suppressible | partially by PisdGMR.PZ

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, suppressible by ItprJF01957/PisdGMR.PZ/Scer\GAL4GMR.long

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, suppressible by porinJF03251/PisdGMR.PZ/Scer\GAL4GMR.long

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, suppressible by PisdGMR.PZ/Scer\GAL4GMR.long/MiroGL01583

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, suppressible by PisdGMR.PZ/Scer\GAL4GMR.long/MiroGL01583

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, suppressible by porinJF03251/PisdGMR.PZ/Scer\GAL4GMR.long

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, suppressible by ItprJF01957/PisdGMR.PZ/Scer\GAL4GMR.long

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has retina | somatic clone phenotype, suppressible by Hsap\PCYT2GMR.PZ

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, suppressible by Hsap\PCYT2GMR.PZ

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, suppressible by Hsap\PCYT2GMR.PZ

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, suppressible by Hsap\PCYT2ninaE.PZ

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, suppressible by Hsap\PCYT2ninaE.PZ

      (Zhao and Wang, 2020)
      NOT suppressed by
      Statement
      Reference

      Pect29, Scer\FLP1ey.PU has retina | somatic clone phenotype, non-suppressible by rdgAGMR.PZ

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has retina | somatic clone phenotype, non-suppressible by laza1

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, non-suppressible by rdgAGMR.PZ

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, non-suppressible by rdgAGMR.PZ

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, non-suppressible by laza1

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, non-suppressible by laza1

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, non-suppressible by norpAP24

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, non-suppressible by norpAP24

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, non-suppressible by Scer\GAL4GMR.long/PisJF03315

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, non-suppressible by Scer\GAL4GMR.long/PisJF03315

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, non-suppressible by trp9

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, non-suppressible by Df(1)inaF-P106x

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, non-suppressible by trp9

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, non-suppressible by Df(1)inaF-P106x

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, non-suppressible by Pcyt1[+]/Pcyt1179

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, non-suppressible by Pcyt1[+]/Pcyt1179

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, non-suppressible by Pcyt1GMR.PZ

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, non-suppressible by bbcGMR.PZ

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, non-suppressible by Pcyt1GMR.PZ

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, non-suppressible by bbcGMR.PZ

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, non-suppressible by PisdGMR.PZ/MarfHMC03883/Scer\GAL4GMR.long

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, non-suppressible by PisdGMR.PZ/MarfHMC03883/Scer\GAL4GMR.long

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has eye photoreceptor cell | somatic clone | decreased number phenotype, non-suppressible by PisdGMR.PZ/SERCAHMS02878/Scer\GAL4GMR.long

      (Zhao and Wang, 2020)

      Pect29, Scer\FLP1ey.PU has rhabdomere | somatic clone | decreased number phenotype, non-suppressible by PisdGMR.PZ/SERCAHMS02878/Scer\GAL4GMR.long

      (Zhao and Wang, 2020)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of PisdGMR.PZ partially suppresses the ERG phenotype of Pect29 (in combination with Scer\FLP1[ey.PU]) in nine-day-old adults while it fails to suppress in one-day-old flies.

      (Zhao and Wang, 2020)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Pect29 is rescued by PectGMR.PZ

      (Zhao and Wang, 2020)

      Pect29 is rescued by PectninaE.PZ

      (Zhao and Wang, 2020)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Pect29
      pect29
      (Zhao and Wang, 2020)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)