FB2026_03 , released September 17, 2026
Allele: Dmel\gdrd1
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General Information
Symbol
Dmel\gdrd1
Species
D. melanogaster
Name
FlyBase ID
FBal0367275
Feature type
allele
Associated gene
Dmel\gdrd
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Lange et al., 2021)
Mutagen
CRISPR/Cas9
(Lange et al., 2021)
Progenitor genotype
Cytology
Description

A 1.27kb segment is deleted from endogenous gdrd.

(Lange et al., 2021)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
3L:14,690,785..14,692,057 [+]
Comment:

A 1.27kb segment is deleted from endogenous gdrd. Six bases (CCCACA) are present at the site of the deletion.

Inserted_sequence:

CCCACA

(Patel et al., 2021.7.22)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      gdrd1 homozygotes exhibit empty seminal vesicles, lack mature sperm; testes exhibit fewer individualization complexes, which fail to progress through the length of the sperm; fewer nuclear bundles are undergoing individualization; waste bags are absent.

      (Lange et al., 2021)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      gdrd1 is rescued by gdrdTag:HA

      (Lange et al., 2021)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      gdrd1
      (Lange et al., 2021)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)