FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Tmem631
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General Information
Symbol
Dmel\Tmem631
Species
D. melanogaster
Name
FlyBase ID
FBal0367965
Feature type
allele
Associated gene
Dmel\Tmem63
Associated Insertion(s)
TI{TI}Tmem631
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Li and Montell, 2021)
Mutagen
ends-out gene targeting
(Li and Montell, 2021)
Progenitor genotype
Associated Insertion(s)
TI{TI}Tmem631
Cytology
Description

The first three of eleven transmembrane segments (sequences 16-1026) are replaced with an insertion consisting of mini-white and GAL4, which is out-of-frame (23 base pairs after the Tmem63 start codon) and therefore not expressed.

(Li and Montell, 2021)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
2R:8,099,579..8,100,564 [+]
Comment:

The first three of eleven transmembrane segments are replaced with an insertion consisting of mini-white and Scer\GAL4, which is out-of-frame and therefore not expressed. Position of deletion endpoints on reference sequence determined from reported primer sequences.

(Li and Montell, 2021.7.27)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Tmem631
      tmem631
      (Li and Montell, 2021)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)