FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\inaEExc.90.1
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General Information
Symbol
Dmel\inaEExc.90.1
Species
D. melanogaster
Name
FlyBase ID
FBal0368861
Feature type
allele
Associated gene
Dmel\inaE
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Tortoriello et al., 2021)
Progenitor genotype
P{SUPor-P}inaEKG08585
(Tortoriello et al., 2021)
Cytology
Description

Deletion within inaE; removes most of the catalytic domain. Generated by imprecise excision of P{SUPor-P}inaEKG08585.

(Tortoriello et al., 2021)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
X:13,803,754..13,806,582 [+]
Comment:

Deletion resulting from the imprecise excision of P{SUPor-P}inaEKG08585, which removes sequences from exon 9 to 14 of inaE (relatife to inaE-RD)..

(Williams and Doherty, 2021.8.15)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      inaEExc.90.1 homozygotes show a developmental delay as compared to controls. Stage 16 embryonic SNb neurons show axon stalling, defasciculation, and misrouting, with inappropriate contacts.

      (Tortoriello et al., 2021)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      inaEExc.90.1
      (Tortoriello et al., 2021)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)