FB2026_02 , released June 18, 2026
Allele: Dmel\robo2ΔIg1.4xHA
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General Information
Symbol
Dmel\robo2ΔIg1.4xHA
Species
D. melanogaster
Name
FlyBase ID
FBal0369742
Feature type
allele
Associated gene
Dmel\robo2
Associated Insertion(s)
TI{TI}robo2ΔIg1.4xHA
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Howard et al., 2021)
gene targeting by homologous recombination
(Howard et al., 2021)
Progenitor genotype
Associated Insertion(s)
TI{TI}robo2ΔIg1.4xHA
Cytology
Description

Exons 2-14 of the endogenous robo2 locus have been replaced by robo2 cDNA sequence that lacks the Ig1 domain and in which the coding sequence is tagged at the N-terminal end with 4xTag:HA. The endogenous robo2 promoter, transcriptional start site, first exon (including the start codon and signal sequence) and first intron remain unmodified.

(Howard et al., 2021)
Allele components
Component
Use(s)
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      robo2robo2ΔIg1
      (Howard et al., 2021)
      robo2ΔIg1.4xHA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)