FlyBase Allele Report: Dmel\Rab30[Gal4-KO]

General Information

Symbol

Dmel\Rab30^Gal4-KO

Species

D. melanogaster

Name

FlyBase ID

FBal0370486

Feature type

allele

Associated gene

Dmel\Rab30

Associated Insertion(s)

TI{GAL4}Rab30^Gal4-KO

Carried in Construct

Key Links

Allele class

amorphic allele - molecular evidence

Mutagen

ends-out gene targeting

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Kohrs et al., 2021)

Mutagen

ends-out gene targeting

(Kohrs et al., 2021)

Progenitor genotype

Associated Insertion(s)

TI{GAL4}Rab30^Gal4-KO

Cytology

Description

The open reading frame of endogenous Rab30 is replaced with a GAL4 driver coding region and a loxP cassette containing both Disc\RFP^3xP3.PC and the kanamycin resistance gene.

(Kohrs et al., 2021)

Allele components

Component

Use(s)

Inserted element

TI{GAL4}

promoter trap

Encoded product / tool

GAL4

binary expression system - driver

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neurophysiology | adult stage

(Kohrs et al., 2021)

decreased size | adult stage

(Kohrs et al., 2021)

lethal | parental effect

(Kohrs et al., 2021)

male sterile

(Kohrs et al., 2021)

viable

(Kohrs et al., 2021)

Phenotype Manifest In

outer photoreceptor cell | adult stage

(Kohrs et al., 2021)

retina

(Kohrs et al., 2021)

rhabdomere of eye photoreceptor cell | adult stage

(Kohrs et al., 2021)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Rab30^Gal4-KO is rescued by Rab30^UASp.YFP/Scer\GAL4^{Rab30-Gal4-KO}

(Kohrs et al., 2021)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Rab30^Gal4-KO

rab30^-Gal4-KI

(Kohrs et al., 2021)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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