FB2026_02 , released June 18, 2026
Allele: Scer\GAL4AD.R83E12
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General Information
Symbol
Scer\GAL4AD.R83E12
Species
S. cerevisiae
Name
FlyBase ID
FBal0371200
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{R83E12-GAL4.AD}
Also Known As
83E12-Gal4AD
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Pogodalla et al., 2021)
Progenitor genotype
Carried in construct
P{R83E12-GAL4.AD}
Cytology
Description

The GMR83E12 enhancer regulates expression of a GAL4(AD)::Zip+ hemidriver (component of a 'split driver' system, contains the GAL4 activation domain).

(Pogodalla et al., 2021)
Allele components
Component
Use(s)
Regulatory region(s)
GMR83E12
Encoded product / tool
GAL4(AD)::Zip+
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      embryonic/larval ensheathing glial cell

      Comment: when combined with P{repo-GAL4.DBD}

      (Pogodalla et al., 2021)
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The genetic ablation of ensheathing glia by the co-expression of hidUAS.cZa and rprUAS.C under combined control of Scer\GAL4AD.R83E12 and Scer\GAL4DBD.repo leads to heat-induced paralysis (2min at 40[o]C); individuals also show increased day-time sleep.

      (Yildirim et al., 2022)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4AD.R83E12
      Name Synonyms
      Secondary FlyBase IDs
        References (3)