FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\srpΔsrpNC
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General Information
Symbol
Dmel\srpΔsrpNC
Species
D. melanogaster
Name
FlyBase ID
FBal0373597
Feature type
allele
Associated gene
Dmel\srp
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Moussalem et al., 2021)
Progenitor genotype
Cytology
Description

Deletion of most of srp exon 4A (this exon encodes the N-terminal zinc finger domain of the NC isoform), resulting in a locus that can only produce the srp C isoform.

(Moussalem et al., 2021)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
3R:16,000,569..16,000,780 [+]
Comment:

Deletion of most of one of the two srp alternatively spliced exons. This exon encodes the N-terminal zinc finger domain of certain isoforms. This resulting in a locus that can only produce isoforms containing the second of the alternatively spliced exons.

(Moussalem et al., 2021)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      srpΔsrpNC
      (Moussalem et al., 2021)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)