FB2026_03 , released September 17, 2026
Allele: Dmel\cnoΔPDZ.GFP
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General Information
Symbol
Dmel\cnoΔPDZ.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0373699
Feature type
allele
Associated gene
Dmel\cno
Associated Insertion(s)
TI{TI}cnoΔPDZ.GFP
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Perez-Vale et al., 2021)
gene targeting by homologous recombination
(Perez-Vale et al., 2021)
cre recombinase
(Perez-Vale et al., 2021)
Progenitor genotype
TI{TI}cnoΔPDZ.GFP+ΔRA
(Perez-Vale et al., 2021)
Associated Insertion(s)
TI{TI}cnoΔPDZ.GFP
Cytology
Description

The wGMR.PHb and Disc\RFPDsRed(T1).3xP3.cHa markers present downstream of the GFP-tagged 'ΔPDZ' cno sequence in TI{TI}cnoΔPDZ.GFP+ΔRA have been excised (using P1cre recombinase). The duplicated 3' portion of cno (encoding a truncated cno 'ΔRA' protein) that was present downstream of these two markers in TI{TI}cnoΔPDZ.GFP+ΔRA has also been deleted (using homology-directed repair); this deleted sequence has been replaced by a loxP cassette containing a Disc\RFPDsRed(T1).3xP3.cHa marker. This results in a chromosome that expresses GFP-tagged cno that lacks the PDZ domain (amino acid residues 1006-1099 are missing).

(Perez-Vale et al., 2021)
Allele components
Component
Use(s)
Tagged with
GFP
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      cnoΔPDZ.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)