Nucleotide changes (AGGTGAGTGC to AGGTCTTCTC) in the splice donor sequence of the first of the two ratchet points present in the approximately 50kb intron 3 of kuz.
CTTCTCTTT
CTTCTCTTT replaces GAGTG in the splice donor sequence of the first of the two ratchet points present in the approximately 50kb intron of kuz.