FB2026_03 , released September 17, 2026
Allele: Dmel\Dscam1BM2
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General Information
Symbol
Dmel\Dscam1BM2
Species
D. melanogaster
Name
FlyBase ID
FBal0374273
Feature type
allele
Associated gene
Dmel\Dscam1
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Dong et al., 2022)
gene targeting by homologous recombination
(Dong et al., 2022)
Progenitor genotype
Cytology
Description

Two sets of mutations within Dscam1. The first is a deletion of 'Ubs6.1' (upstream balancer sequence 6.1), a sequence located in the upstream intron-exon 6.1 boundary region and whose wild-type sequence is highly complementary to the conserved 'Dbs6.40' (downstream balancer sequence 6.40) intronic element located upstream of exon 6.40. The second is a mutation of the 5' splice site of the intron immediately downstream of exon 6.1.

(Dong et al., 2022)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
MNV
2R:7,360,525..7,360,526 [-]
Nucleotide change:

GG7360526AC

Reported nucleotide change:

GG?AC

Comment:

One of two mutations within Dscam1. The second is a mutation of the 5' splice site of the intron immediately downstream of exon 6.1.

(Dong et al., 2022)
delins
2R:7,360,633..7,360,657 [-]
Comment:

First of two mutations within Dscam1. A deletion/insertion of 'Ubs6.1'.

Inserted_sequence:

GTCGAC

(Dong et al., 2022)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
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      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Dscam1BM2
      DscamBM2
      (Dong et al., 2022)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)