FB2026_02 , released June 18, 2026
Allele: Dmel\YpeChi-A
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General Information
Symbol
Dmel\YpeChi-A
Species
D. melanogaster
Name
FlyBase ID
FBal0374593
Feature type
allele
Associated gene
Dmel\Ype
Associated Insertion(s)
TI{TI}YpeChi-A
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Dean et al., 2022)
gene targeting by homologous recombination
(Dean et al., 2022)
Progenitor genotype
Associated Insertion(s)
TI{TI}YpeChi-A
Cytology
Description

Deletion of sequence from -9 to -37 relative to the Ype transcription start site. Associated with this deletion, a sequence cassette that includes a w+* marker, donor plasmid sequence (AmpR and ColE1 sequence) and a single 48bp FRT site has been inserted 28bp upstream of the Ype 5'UTR. Sequence in the 3'UTR has been changed from GGCCATCTACTCaatacttAGGG to GGCCATCTACTCtaccctataAGGG.

(Dean et al., 2022)
Allele components
Component
Use(s)
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
X:13,387,380..13,387,408 [-]
Comment:

Deletion of sequences from -9 to -37 relative to the Ype transcription start. One of three alterations in mutant.

(Dean et al., 2022)
delins
X:13,386,277..13,386,283 [-]
Comment:

Reported as a change from GGCCATCTACTCaatacttAGGG-> GGCCATCTACTCtaccctataAGGG (on the noncoding strand). One of three alterations in mutant.

Inserted_sequence:

TATAGGGTA

(Hope et al., 2022)
insertion
X:13,387,445..13,387,446 [-]
Comment:

Insertion of a 5,600bp sequence cassette that includes a w+* marker, donor plasmid sequence (AmpR and ColE1 sequence) and a single 48bp FRT site 28bp upstream of the Ype 5'UTR. One of three alterations in mutant.

(Dean et al., 2022)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      YpeChi-A leads to an incompletely dominant dark body color in females. YpeChi-A males exhibit a dark body color, curved wings, ectopic scutellar bristles, and exhibit difficulty in emerging from the pupal case. YpeChi-A/Ypes1 females exhibit a dark body color and ectopic scutellar bristles.

      (Dean et al., 2022)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      Ypes-1

      (Dean et al., 2022)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      YippeeChi-A
      (Dean et al., 2022)
      YpeChi-A
      Name Synonyms
      Secondary FlyBase IDs
        References (1)