FlyBase Allele Report: Dmel\Ir56b[GAL4]

General Information

Symbol

Dmel\Ir56b^GAL4

Species

D. melanogaster

Name

FlyBase ID

FBal0374595

Feature type

allele

Associated gene

Dmel\Ir56b

Associated Insertion(s)

TI{GAL4}Ir56b^GAL4

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

CRISPR/Cas9

(Dweck et al., 2022)

gene targeting by homologous recombination

(Dweck et al., 2022)

Progenitor genotype

Associated Insertion(s)

TI{GAL4}Ir56b^GAL4

Cytology

Description

Sequence encoding the 1. GAL4 driver, 2. a Disc\RFP^{DsRed(T1).3xP3.cHa} marker flanked by loxP sites and 3. a single attP site has been inserted into the endogenous Ir56b locus, replacing the Ir56b coding sequence.

(Dweck et al., 2022)

Allele components

Component

Use(s)

Inserted element

TI{GAL4}

promoter trap

Encoded product / tool

GAL4

binary expression system - driver

Also carries

attP

integrase target site

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neurophysiology | adult stage

(Dweck et al., 2022)

abnormal proboscis extension reflex

(Dweck et al., 2022)

Phenotype Manifest In

L-type sensillum L1

(Dweck et al., 2022)

short labellar taste bristle S-c

(Dweck et al., 2022)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Ir56b^GAL4 has abnormal neurophysiology | adult stage phenotype, suppressible by Scer\GAL4^Ir56b-GAL4/Dere\Ir56b^UAS.cDa

(Dweck et al., 2022)

Ir56b^GAL4 has abnormal neurophysiology | adult stage phenotype, suppressible by Dsuz\Ir56b^UAS.cDa/Scer\GAL4^Ir56b-GAL4

(Dweck et al., 2022)

Ir56b^GAL4 has abnormal neurophysiology | adult stage phenotype, suppressible by Dvir\Ir56b^UAS.cDa/Scer\GAL4^Ir56b-GAL4

(Dweck et al., 2022)

Ir56b^GAL4 has abnormal neurophysiology | adult stage phenotype, suppressible by Scer\GAL4^Ir56b-GAL4/Dsec\Ir56b^UAS.cDa

(Dweck et al., 2022)

Ir56b^GAL4 has abnormal neurophysiology | adult stage phenotype, suppressible by Scer\GAL4^Ir56b-GAL4/Dsim\Ir56b^UAS.cDa

(Dweck et al., 2022)

Phenotype Manifest In

Suppressed by

Statement

Reference

Ir56b^GAL4 has short labellar taste bristle S-c phenotype, suppressible by Scer\GAL4^Ir56b-GAL4/Dere\Ir56b^UAS.cDa

(Dweck et al., 2022)

Ir56b^GAL4 has short labellar taste bristle S-c phenotype, suppressible by Dsuz\Ir56b^UAS.cDa/Scer\GAL4^Ir56b-GAL4

(Dweck et al., 2022)

Ir56b^GAL4 has short labellar taste bristle S-c phenotype, suppressible by Scer\GAL4^Ir56b-GAL4/Dsec\Ir56b^UAS.cDa

(Dweck et al., 2022)

Ir56b^GAL4 has short labellar taste bristle S-c phenotype, suppressible by Scer\GAL4^Ir56b-GAL4/Dsim\Ir56b^UAS.cDa

(Dweck et al., 2022)

Ir56b^GAL4 has short labellar taste bristle S-c phenotype, suppressible by Dvir\Ir56b^UAS.cDa/Scer\GAL4^Ir56b-GAL4

(Dweck et al., 2022)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Ir56b^GAL4 is rescued by Ir56b^TTC.UAS/Scer\GAL4^Ir56b-GAL4

(Dweck et al., 2022)

Ir56b^GAL4 is rescued by Scer\GAL4^Ir56b-GAL4/Ir56b^UAS.cDa

(Dweck et al., 2022)

Not rescued by

Ir56b^GAL4 is not rescued by Scer\GAL4^Ir56b-GAL4/Ir56b^Δ462.UAS

(Dweck et al., 2022)

Ir56b^GAL4 is not rescued by Ir56b^Δ51.UAS/Scer\GAL4^Ir56b-GAL4

(Dweck et al., 2022)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Ir56b^GAL4

(Dweck et al., 2022)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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