FB2026_02 , released June 18, 2026
Allele: Dmel\DiedelΔ2
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General Information
Symbol
Dmel\DiedelΔ2
Species
D. melanogaster
Name
FlyBase ID
FBal0374752
Feature type
allele
Associated gene
Dmel\Diedel
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Mlih and Karpac, 2022)
Mutagen
CRISPR/Cas9
(Mlih and Karpac, 2022)
Progenitor genotype
Cytology
Description

A five nucleotide deletion in Diedel leads to a frameshift in translation.

(Mlih and Karpac, 2022)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3R:29,493,909..29,493,913 [+]
Comment:

A 5bp deletion starting in codon 11 of Diedel leads to a frameshift.

(Mlih and Karpac, 2022)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      DiedelΔ1/DiedelΔ2 transheterozygotes present adult midgut epithelium defects, namely enterocyte detachment from the basement membrane and increased mitotic index.

      (Mlih and Karpac, 2022)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      DiedelΔ2
      dieΔ2
      (Mlih and Karpac, 2022)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)