FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Dnaaf6Venus
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General Information
Symbol
Dmel\Dnaaf6Venus
Species
D. melanogaster
Name
FlyBase ID
FBal0376117
Feature type
allele
Associated gene
Dmel\Dnaaf6
Associated Insertion(s)
Carried in Construct
P{Dnaaf6-mVenus}
Key Links
Transgenic product class
genomic_DNA
(Lennon et al., 2022)
wild_type
(Lennon et al., 2022)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Lennon et al., 2022)
wild_type
(Lennon et al., 2022)
Mutagen
in vitro construct
(Lennon et al., 2022)
Progenitor genotype
Carried in construct
P{Dnaaf6-mVenus}
Cytology
Description

Dnaaf6 genomic DNA (including introns, 5' UTR, TSS, and additional upstream flanking DNA of approximately 1 kb, but lacking the stop codon) is fused in-frame with the mVenus coding sequence.

(Lennon et al., 2022)
Allele components
Component
Use(s)
Regulatory region(s)
Dnaaf6
Encoded product / tool
Dnaaf6
Tagged with
Venus
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage
      chordotonal neuron
      (Lennon et al., 2022)
      pupal stage
      Johnston organ neuron
      (Lennon et al., 2022)
      adult stage | male
      spermatocyte
      (Lennon et al., 2022)
      spermatid
      (Lennon et al., 2022)
      Additional Information
      Statement
      Reference

      Dnaaf6 is expressed exclusively in motile ciliated cells. The Venus reporter is observed in embryonic chordotonal neurons, in the differentiating chordotonal neurons of Johnston's organ in the pupal antenna, and also in developing spermatocytes and spermatids.

      (Lennon et al., 2022)
       
      Marker for
      Reflects expression of
      Dnaaf6
      (Lennon et al., 2022)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescued by

      FBal0376117:, Dnaaf6null is partially rescued by Dnaaf6Venus/Dnaaf6Venus

      (Lennon et al., 2022)
      Partially rescues

      Dnaaf6Venus/Dnaaf6Venus partially rescues FBal0376117:, Dnaaf6null

      (Lennon et al., 2022)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Dnaaf6Venus
      Name Synonyms
      Secondary FlyBase IDs
        References (1)