FlyBase Allele Report: Hsap\MTMR2[UAS.cHa]

General Information

Symbol

Hsap\MTMR2^UAS.cHa

Species

H. sapiens

Name

UAS construct a of Hu

FlyBase ID

FBal0386325

Feature type

allele

Associated gene

Hsap\MTMR2

Associated Insertion(s)

Carried in Construct

P{UAS-hMTMR2.H}

Key Links

Transgenic product class

cDNA

(Hu et al., 2022)

wild_type

(Hu et al., 2022)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Hu et al., 2022)

wild_type

(Hu et al., 2022)

Mutagen

in vitro construct

(Hu et al., 2022)

Progenitor genotype

Carried in construct

P{UAS-hMTMR2.H}

Cytology

Description

UASt regulatory sequences drive expression of full-length Hsap\MTMR2.

(Hu et al., 2022)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Hsap\MTMR2

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates Charcot-Marie-Tooth disease type 4B1

modeled by mtm^G447D

(Hu et al., 2022)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^αTub84B.PL/Hsap\MTMR2^UAS.cHa is a suppressor | partially of increased cell number | P-stage | somatic clone - tissue specific phenotype of ex^e1, mtm^null

(Hu et al., 2022)

Scer\GAL4^αTub84B.PL/Hsap\MTMR2^UAS.cHa is a suppressor | partially of increased size | somatic clone | adult stage phenotype of ex^e1, mtm^null

(Hu et al., 2022)

Scer\GAL4^αTub84B.PL/Hsap\MTMR2^UAS.cHa is a suppressor of lethal - all die before end of second instar larval stage phenotype of mtm^null

(Hu et al., 2022)

Scer\GAL4^αTub84B.PL/Hsap\MTMR2^UAS.cHa is a suppressor of increased cell number | P-stage | somatic clone - tissue specific phenotype of mtm^null

(Hu et al., 2022)

Scer\GAL4^αTub84B.PL/Hsap\MTMR2^UAS.cHa is a suppressor | partially of increased cell number | P-stage | somatic clone - tissue specific phenotype of ft⁸, mtm^null

(Hu et al., 2022)

Scer\GAL4^αTub84B.PL/Hsap\MTMR2^UAS.cHa is a suppressor | partially of increased size | somatic clone | adult stage phenotype of ft⁸, mtm^null

(Hu et al., 2022)

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^αTub84B.PL/Hsap\MTMR2^UAS.cHa is a suppressor | partially of mesonotum | somatic clone | adult stage phenotype of ft⁸, mtm^null

(Hu et al., 2022)

Scer\GAL4^αTub84B.PL/Hsap\MTMR2^UAS.cHa is a suppressor of eye disc | somatic clone | larval stage phenotype of mtm^null

(Hu et al., 2022)

Scer\GAL4^αTub84B.PL/Hsap\MTMR2^UAS.cHa is a suppressor | partially of interommatidial cell | increased number | P-stage | somatic clone - tissue specific phenotype of ex^e1, mtm^null

(Hu et al., 2022)

Scer\GAL4^αTub84B.PL/Hsap\MTMR2^UAS.cHa is a suppressor | partially of mesonotum | somatic clone | adult stage phenotype of ex^e1, mtm^null

(Hu et al., 2022)

Scer\GAL4^αTub84B.PL/Hsap\MTMR2^UAS.cHa is a suppressor of interommatidial cell | increased number | P-stage | somatic clone - tissue specific phenotype of mtm^null

(Hu et al., 2022)

Scer\GAL4^αTub84B.PL/Hsap\MTMR2^UAS.cHa is a suppressor | partially of interommatidial cell | increased number | P-stage | somatic clone - tissue specific phenotype of ft⁸, mtm^null

(Hu et al., 2022)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Hsap\MTMR2^UAS.cHa

Name Synonyms

UAS construct a of Hu

Secondary FlyBase IDs

References (1)

Report Sections

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