FlyBase Allele Report: Dmel\trol[JO271.49]

General Information

Symbol

Dmel\trol^JO271.49

Species

D. melanogaster

Name

FlyBase ID

FBal0386335

Feature type

allele

Associated gene

Dmel\trol

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

loss of function allele

Mutagen

P-element activity

Nature of the Allele

Allele class

loss of function allele

(Bonche et al., 2022)

Mutagen

P-element activity

(Bonche et al., 2022)

Progenitor genotype

P{lacW}trol^G0271

(Bonche et al., 2022)

Cytology

Description

Imprecise excision of P{lacW}trol^G0271 results in a deletion of approximately 5kb within trol, from the end of intron 9 to the beginning of intron 11.

(Bonche et al., 2022)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell shape | larval stage

(Bonche et al., 2022)

decreased cell size | larval stage

(Bonche et al., 2022)

decreased size | larval stage

(Bonche et al., 2022)

some die during P-stage

(Bonche et al., 2022)

visible | adult stage

(Bonche et al., 2022)

visible | P-stage

(Bonche et al., 2022)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

trol^JO271.49 has decreased cell size | larval stage phenotype, suppressible by vkg⁰¹²⁰⁹

(Bonche et al., 2022)

trol^JO271.49 has visible | P-stage phenotype, suppressible by vkg⁰¹²⁰⁹

(Bonche et al., 2022)

trol^JO271.49 has visible | adult stage phenotype, suppressible by vkg⁰¹²⁰⁹

(Bonche et al., 2022)

trol^JO271.49 has increased mortality during development phenotype, suppressible | partially by vkg⁰¹²⁰⁹

(Bonche et al., 2022)

trol^JO271.49 has decreased size | larval stage phenotype, suppressible by vkg⁰¹²⁰⁹

(Bonche et al., 2022)

trol^JO271.49 has decreased size | larval stage phenotype, suppressible by Pxn^f07229

(Bonche et al., 2022)

trol^JO271.49 has decreased size | larval stage phenotype, suppressible | partially by Loxl1^ΔA38

(Bonche et al., 2022)

trol^JO271.49 has decreased size | larval stage phenotype, suppressible | partially by Scer\GAL4^coro-409/Mmp2^UAS.cPa

(Bonche et al., 2022)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

trol^JO271.49 has squamous epithelium | larval stage phenotype, non-enhanceable by Pxn^f07229

(Bonche et al., 2022)

trol^JO271.49 has cuboidal/columnar epithelium | larval stage phenotype, non-enhanceable by Pxn^f07229

(Bonche et al., 2022)

trol^JO271.49 has basement membrane | larval stage phenotype, non-enhanceable by Pxn^f07229

(Bonche et al., 2022)

trol^JO271.49 has wing disc | larval stage phenotype, non-enhanceable by Pxn^f07229

(Bonche et al., 2022)

trol^JO271.49 has wing pouch | larval stage phenotype, non-enhanceable by Pxn^f07229

(Bonche et al., 2022)

trol^JO271.49 has wing disc | larval stage phenotype, non-enhanceable by Scer\GAL4^C-765/Mmp2^UAS.cPa

(Bonche et al., 2022)

Suppressed by

Statement

Reference

trol^JO271.49 has squamous epithelium | larval stage phenotype, suppressible | partially by Loxl1^ΔA38

(Bonche et al., 2022)

trol^JO271.49 has cuboidal/columnar epithelium | larval stage phenotype, suppressible | partially by Loxl1^ΔA38

(Bonche et al., 2022)

trol^JO271.49 has basement membrane | larval stage phenotype, suppressible | partially by Loxl1^ΔA38

(Bonche et al., 2022)

trol^JO271.49 has cuboidal/columnar epithelium | larval stage phenotype, suppressible | partially by Scer\GAL4^coro-409/Mmp2^UAS.cPa

(Bonche et al., 2022)

trol^JO271.49 has squamous epithelium | larval stage phenotype, suppressible | partially by Scer\GAL4^coro-409/Mmp2^UAS.cPa

(Bonche et al., 2022)

trol^JO271.49 has basement membrane | larval stage phenotype, suppressible | partially by Scer\GAL4^coro-409/Mmp2^UAS.cPa

(Bonche et al., 2022)

trol^JO271.49 has wing disc | larval stage phenotype, suppressible | partially by Scer\GAL4^coro-409/Mmp2^UAS.cPa

(Bonche et al., 2022)

trol^JO271.49 has wing pouch | larval stage phenotype, suppressible | partially by Loxl1^ΔA38

(Bonche et al., 2022)

trol^JO271.49 has wing pouch | larval stage phenotype, suppressible | partially by Scer\GAL4^coro-409/Mmp2^UAS.cPa

(Bonche et al., 2022)

trol^JO271.49 has squamous epithelium | larval stage phenotype, suppressible by vkg⁰¹²⁰⁹

(Bonche et al., 2022)

trol^JO271.49 has cuboidal/columnar epithelium | larval stage phenotype, suppressible | partially by vkg⁰¹²⁰⁹

(Bonche et al., 2022)

trol^JO271.49 has wing | P-stage phenotype, suppressible by vkg⁰¹²⁰⁹

(Bonche et al., 2022)

trol^JO271.49 has wing | adult stage phenotype, suppressible by vkg⁰¹²⁰⁹

(Bonche et al., 2022)

NOT suppressed by

Statement

Reference

trol^JO271.49 has squamous epithelium | larval stage phenotype, non-suppressible by Pxn^f07229

(Bonche et al., 2022)

trol^JO271.49 has cuboidal/columnar epithelium | larval stage phenotype, non-suppressible by Pxn^f07229

(Bonche et al., 2022)

trol^JO271.49 has basement membrane | larval stage phenotype, non-suppressible by Pxn^f07229

(Bonche et al., 2022)

trol^JO271.49 has wing disc | larval stage phenotype, non-suppressible by Pxn^f07229

(Bonche et al., 2022)

trol^JO271.49 has wing disc | larval stage phenotype, non-suppressible by Scer\GAL4^C-765/Mmp2^UAS.cPa

(Bonche et al., 2022)

trol^JO271.49 has wing pouch | larval stage phenotype, non-suppressible by Pxn^f07229

(Bonche et al., 2022)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

trol^JO271#49

(Bonche et al., 2022)

trol^JO271.49

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections