FB2026_02 , released June 18, 2026
Allele: Dmel\alka1
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General Information
Symbol
Dmel\alka1
Species
D. melanogaster
Name
FlyBase ID
FBal0389672
Feature type
allele
Associated gene
Dmel\alka
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Mi et al., 2023)
Mutagen
CRISPR/Cas9
(Mi et al., 2023)
Progenitor genotype
Cytology
Description

All four transmembrane segments (TM1-TM4) are deleted in endogenous alka.

(Mi et al., 2023)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2R:10,828,634..10,829,758 [-]
Comment:

A 1125bp deletion removing a portion of the N-terminus, all four transmembrane segments, and the entire C-terminus of the alka protein.

(Mi et al., 2023)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      alka1 has abnormal chemosensory behavior | adult stage phenotype, suppressible | partially by Ir76b1

      (Mi et al., 2023)

      alka1 has abnormal proboscis extension reflex phenotype, suppressible | partially by Ir76b1

      (Mi et al., 2023)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      alka1 is rescued by alkaUAS.cMa/Scer\GAL4alka.PM

      (Mi et al., 2023)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      alka1
      (Mi et al., 2023)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)