FlyBase Allele Report: Dmel\ntc[UAS.cSa]

General Information

Symbol

Dmel\ntc^UAS.cSa

Species

D. melanogaster

Name

FlyBase ID

FBal0391111

Feature type

allele

Associated gene

Dmel\ntc

Associated Insertion(s)

Carried in Construct

P{UAS-ntc.S}

Key Links

Transgenic product class

wild_type

(Whitworth, 2023.5.27)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Whitworth, 2023.5.27)

Mutagen

in vitro construct

(Whitworth, 2023.5.27)

Progenitor genotype

Carried in construct

P{UAS-ntc.S}

Cytology

Description

UAS regulatory sequences drive expression of wild-type ntc.

(Whitworth, 2023.5.27)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

ntc

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates Parkinson's disease 2

modeled by park²⁵

(Sanchez-Martinez et al., 2023)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Scer\GAL4^da.G32/ntc^UAS.cSa is a non-enhancer of decreased rate of adult locomotory behavior phenotype of Pink1^B9

(Sanchez-Martinez et al., 2023)

Scer\GAL4^da.G32/ntc^UAS.cSa is a non-enhancer of decreased rate of flight behavior phenotype of Pink1^B9

(Sanchez-Martinez et al., 2023)

ntc^UAS.cSa, Scer\GAL4^GMR.PF is a non-enhancer of visible | adult stage phenotype of Pink1^UAS.cUa, Scer\GAL4^GMR.PF

(Sanchez-Martinez et al., 2023)

Suppressor of

Statement

Reference

Scer\GAL4^Act5C.PI/ntc^UAS.cSa is a suppressor of decreased rate of adult locomotory behavior phenotype of Scer\GAL4^Act5C.PI, Usp30^UAS.cUa

(Sanchez-Martinez et al., 2023)

Scer\GAL4^da.G32/ntc^UAS.cSa is a suppressor | partially of decreased rate of adult locomotory behavior phenotype of park²⁵

(Sanchez-Martinez et al., 2023)

Scer\GAL4^da.G32/ntc^UAS.cSa is a suppressor of decreased cell number | adult stage phenotype of park²⁵

(Sanchez-Martinez et al., 2023)

NOT Suppressor of

Statement

Reference

Scer\GAL4^da.G32/ntc^UAS.cSa is a non-suppressor of decreased rate of adult locomotory behavior phenotype of Pink1^B9

(Sanchez-Martinez et al., 2023)

Scer\GAL4^da.G32/ntc^UAS.cSa is a non-suppressor of decreased rate of flight behavior phenotype of Pink1^B9

(Sanchez-Martinez et al., 2023)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

ntc^UAS.cSa, Scer\GAL4^GMR.PF is a non-enhancer of eye phenotype of Pink1^UAS.cUa, Scer\GAL4^GMR.PF

(Sanchez-Martinez et al., 2023)

Suppressor of

Statement

Reference

Scer\GAL4^da.G32/ntc^UAS.cSa is a suppressor of dopaminergic PPL1 neuron | adult stage | decreased number phenotype of park²⁵

(Sanchez-Martinez et al., 2023)

Scer\GAL4^da.G32/ntc^UAS.cSa is a suppressor | partially of flight muscle | adult stage phenotype of park²⁵

(Sanchez-Martinez et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^da.G32/ntc^UAS.cSa rescues ntc^ms771

(Sanchez-Martinez et al., 2023)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

99021

w^*; P{UAS-ntc.S}2; Sb¹/TM6B, Tb⁺

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

ntc^UAS.cSa

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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