FlyBase Allele Report: Dmel\Appl[UAS.cPa.Tag:V5]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\Appl^{UAS.cPa.Tag:V5}

General Information

Symbol

Dmel\Appl^{UAS.cPa.Tag:V5}

Species

D. melanogaster

Name

FlyBase ID

FBal0397031

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

P{UAS-Appl.P.V5}

Key Links

Transgenic product class

(Pizzano et al., 2023)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Pizzano et al., 2023)

Mutagen

in vitro construct

(Pizzano et al., 2023)

Progenitor genotype

Carried in construct

P{UAS-Appl.P.V5}

Cytology

Description

UASt regulatory sequences drive expression of Appl tagged with Tag:V5.

(Pizzano et al., 2023)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Tagged with

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates Down syndrome

modeled by Dscam1^{4.3-6.36-9.25-17.2}

(Pizzano et al., 2023)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

axon | larval stage | somatic clone, with Scer\GAL4^ppk.PU

(Pizzano et al., 2023)

larval multidendritic class IV neuron | somatic clone, with Scer\GAL4^ppk.PU

(Pizzano et al., 2023)

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

Appl^{UAS.cPa.Tag:V5}, Scer\GAL4^ppk.PU has larval multidendritic class IV neuron | somatic clone phenotype, enhanceable by Dscam1^{4.3-6.36-9.25-17.2}, Scer\GAL4^ppk.PU

(Pizzano et al., 2023)

Appl^{UAS.cPa.Tag:V5}, Scer\GAL4^ppk.PU has axon | larval stage | somatic clone phenotype, enhanceable by Dscam1^{4.3-6.36-9.25-17.2}, Scer\GAL4^ppk.PU

(Pizzano et al., 2023)

NOT Suppressor of

Statement

Reference

Appl^{UAS.cPa.Tag:V5}/Scer\GAL4^ppk.PU is a non-suppressor of larval multidendritic class IV neuron | somatic clone phenotype of Dscam1¹⁸

(Pizzano et al., 2023)

Appl^{UAS.cPa.Tag:V5}/Scer\GAL4^ppk.PU is a non-suppressor of axon | somatic clone | larval stage phenotype of Dscam1¹⁸

(Pizzano et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Appl^{UAS.cPa.Tag:V5}

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections