FlyBase Allele Report: Dmel\Delta[K2R-HA]

General Information

Symbol

Dmel\Delta^K2R-HA

Species

D. melanogaster

Name

FlyBase ID

FBal0397453

Feature type

allele

Associated gene

Dmel\Delta

Associated Insertion(s)

TI{TI}Delta^K2R-HA

Carried in Construct

Key Links

Allele class

Mutagen

phiC31 integrase

Nature of the Allele

Allele class

Mutagen

phiC31 integrase

(Troost et al., 2023)

Progenitor genotype

TI{TI}Delta^attP

(Troost et al., 2023)

Associated Insertion(s)

TI{TI}Delta^K2R-HA

Cytology

Description

Sequence has been inserted into the attP site present in TI{TI}Delta^attP, reconstituting a transcription unit that encodes full-length Delta in which all K residues of the intracellular domain have been replaced with R residues. In addition, the Delta coding sequence is tagged at the C-terminal end with Tag:HA.

(Troost et al., 2023)

Allele components

Component

Use(s)

Tagged with

Tag:HA

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female semi-sterile

(Troost et al., 2023)

female semi-sterile (with Df(3R)BSC850)

(Troost et al., 2023)

viable (with Df(3R)BSC850)

(Troost et al., 2023)

visible | adult stage

(Troost et al., 2023)

visible | adult stage (with Df(3R)BSC850)

(Troost et al., 2023)

Phenotype Manifest In

egg chamber (with Df(3R)BSC850)

(Troost et al., 2023)

metatarsus

(Troost et al., 2023)

tarsal segment 2

(Troost et al., 2023)

tarsal segment 3

(Troost et al., 2023)

tarsal segment 3 (with Df(3R)BSC850)

(Troost et al., 2023)

tarsal segment 4

(Troost et al., 2023)

tarsal segment 4 (with Df(3R)BSC850)

(Troost et al., 2023)

wing margin

(Troost et al., 2023)

wing vein

(Troost et al., 2023)

wing vein (with Df(3R)BSC850)

(Troost et al., 2023)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Delta^K2R-HA/Df(3R)BSC850 has visible | adult stage phenotype, enhanceable by lqf^unspecified

(Troost et al., 2023)

Suppressed by

Statement

Reference

Delta^K2R-HA has visible | adult stage phenotype, suppressible by lqf^FL.GFP/lqf^FL.GFP

(Troost et al., 2023)

Delta^K2R-HA has visible | adult stage phenotype, suppressible by N^GFP/N^GFP

(Troost et al., 2023)

Suppressor of

Statement

Reference

Delta^K2R-HA/Delta^K2R-HA is a suppressor of visible | adult stage phenotype of N^GFP

(Troost et al., 2023)

Other

Statement

Reference

Delta^K2R-HA/Df(3R)BSC850, lqf^unspecified has visible | adult stage phenotype

(Troost et al., 2023)

Delta^K2R-HA/Df(3R)BSC850, Scer\GAL4^ci.PC, neur^GD4474 has neurogenic phenotype | larval stage phenotype

(Troost et al., 2023)

Phenotype Manifest In

Enhanced by

Statement

Reference

Delta^K2R-HA/Df(3R)BSC850 has wing vein phenotype, enhanceable by lqf^unspecified

(Troost et al., 2023)

Suppressed by

Statement

Reference

Delta^K2R-HA has tarsal segment 3 phenotype, suppressible by N^GFP/N^GFP

(Troost et al., 2023)

Delta^K2R-HA has tarsal segment 4 phenotype, suppressible by N^GFP/N^GFP

(Troost et al., 2023)

Delta^K2R-HA has tarsal segment 2 phenotype, suppressible by N^GFP/N^GFP

(Troost et al., 2023)

Delta^K2R-HA has metatarsus phenotype, suppressible by N^GFP/N^GFP

(Troost et al., 2023)

Delta^K2R-HA has wing vein phenotype, suppressible by N^GFP/N^GFP

(Troost et al., 2023)

Delta^K2R-HA has wing margin phenotype, suppressible by N^GFP/N^GFP

(Troost et al., 2023)

Delta^K2R-HA has tarsal segment 3 phenotype, suppressible by lqf^FL.GFP/lqf^FL.GFP

(Troost et al., 2023)

Delta^K2R-HA has tarsal segment 4 phenotype, suppressible by lqf^FL.GFP/lqf^FL.GFP

(Troost et al., 2023)

Delta^K2R-HA has wing phenotype, suppressible by lqf^FL.GFP/lqf^FL.GFP

(Troost et al., 2023)

Suppressor of

Statement

Reference

Delta^K2R-HA/Delta^K2R-HA is a suppressor of wing vein phenotype of N^GFP

(Troost et al., 2023)

Other

Statement

Reference

Delta^K2R-HA/Df(3R)BSC850, lqf^unspecified has wing margin phenotype

(Troost et al., 2023)

Delta^K2R-HA/Df(3R)BSC850, Scer\GAL4^ci.PC, neur^GD4474 has wing disc | larval stage phenotype

(Troost et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Delta^K2R-HA

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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