FlyBase Allele Report: Dmel\Rab1[RNAi.UAS]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\Rab1^RNAi.UAS

General Information

Symbol

Dmel\Rab1^RNAi.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0397484

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

P{UAS-Rab1.RNAi}

Key Links

Transgenic product class

(Rollins and Blankenship, 2023)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Rollins and Blankenship, 2023)

Mutagen

in vitro construct

(Rollins and Blankenship, 2023)

Progenitor genotype

Carried in construct

P{UAS-Rab1.RNAi}

Cytology

Description

UAS regulatory sequences drive expression of a hairpin (GAGTCTTTCAACAATGTGATAGTTA) that targets Rab1 (pWALIUM22 vector).

(Rollins and Blankenship, 2023)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal mitotic cell cycle | embryonic cycle, with Scer\GAL4^{VP16.mat.αTub67C}

(Rollins and Blankenship, 2023)

increased size | embryonic stage, with Scer\GAL4^{VP16.mat.αTub67C}

(Rollins and Blankenship, 2023)

Phenotype Manifest In

endoplasmic reticulum | embryonic stage, with Scer\GAL4^{VP16.mat.αTub67C}

(Rollins and Blankenship, 2023)

Golgi apparatus | embryonic stage, with Scer\GAL4^{VP16.mat.αTub67C}

(Rollins and Blankenship, 2023)

mitotic spindle | embryonic cycle, with Scer\GAL4^{VP16.mat.αTub67C}

(Rollins and Blankenship, 2023)

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Rab1^RNAi.UAS, Scer\GAL4^{VP16.mat.αTub67C} has abnormal mitotic cell cycle | embryonic cycle phenotype, suppressible by BicD^GL00325, Scer\GAL4^{VP16.mat.αTub67C}

(Rollins and Blankenship, 2023)

Phenotype Manifest In

Suppressed by

Statement

Reference

Rab1^RNAi.UAS, Scer\GAL4^{VP16.mat.αTub67C} has endoplasmic reticulum | embryonic stage phenotype, suppressible by BicD^GL00325, Scer\GAL4^{VP16.mat.αTub67C}

(Rollins and Blankenship, 2023)

Suppressor of

Statement

Reference

Rab1^RNAi.UAS, Scer\GAL4^{VP16.mat.αTub67C} is a suppressor of endoplasmic reticulum | embryonic stage phenotype of BicD^GL00325, Scer\GAL4^{VP16.mat.αTub67C}

(Rollins and Blankenship, 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Rab1^RNAi.UAS

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections