FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Usp10CRISPR.12-2
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General Information
Symbol
Dmel\Usp10CRISPR.12-2
Species
D. melanogaster
Name
FlyBase ID
FBal0398804
Feature type
allele
Associated gene
Dmel\Usp10
Associated Insertion(s)
TI{TI}Usp10CRISPR.12-2
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Farkas et al., 2023)
Mutagen
CRISPR/Cas9
(Farkas et al., 2023)
Progenitor genotype
Associated Insertion(s)
TI{TI}Usp10CRISPR.12-2
Cytology
Description

2bp deletion and 12bp insertion in the first common exon of all three predicted transcripts of Usp10, resulting in a frameshift and premature termination.

(Farkas et al., 2023)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3L:888,904..888,905 [+]
Comment:

A 2bp insertion in the first common exon of Usp10 leads to a frameshift and early translation termination. There is also a 12bp insertion in the mutant. Described as NT_037436.6.49: g. 888904_888905del + 888960_888961insN[12].

(Farkas et al., 2023)
insertion
3L:888,960..888,961 [+]
Comment:

An unspecified 12 bp insertion in the first common exon of Usp10. There is also a 2bp deletion in the mutants. Described as NT_037436.6.49: g. 888904_888905del + 888960_888961insN[12].

Inserted_sequence:

NNNNNNNNNNNN

(Farkas et al., 2023)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Usp10<up>CRISPR 12/2</up>
      (Farkas et al., 2023)
      Usp10CRISPR.12-2
      Name Synonyms
      Secondary FlyBase IDs
        References (1)