FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\scbKO
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General Information
Symbol
Dmel\scbKO
Species
D. melanogaster
Name
FlyBase ID
FBal0398930
Feature type
allele
Associated gene
Dmel\scb
Associated Insertion(s)
TI{TI}scbKO
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Collinet et al., 2024)
Mutagen
CRISPR/Cas9
(Collinet et al., 2024)
gene targeting by homologous recombination
(Collinet et al., 2024)
Progenitor genotype
Associated Insertion(s)
TI{TI}scbKO
Cytology
Description

Deletion that extends from -281 to +8670bp relative to the ATG of the scb-RB transcript (this removes the entire open reading frame and part of the 5' and 3' UTRs). A single attP site and a single loxP site are inserted in place of the deleted sequence.

(Collinet et al., 2024)
Allele components
Component
Use(s)
Also carries
attP
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
2R:15,249,015..15,257,965 [+]
Comment:

A deletion that extends from -281 to +8670bp relative to the ATG of the scb-RB transcript. The deleted sequence is replaced with a single attP site and a single loxP.

(Philippe et al., 2024.3.20)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      scabKO
      (Collinet et al., 2024)
      scbKO
      Name Synonyms
      Secondary FlyBase IDs
        References (2)