FlyBase Allele Report: Dmel\Rer1[KO]

General Information

Symbol

Dmel\Rer1^KO

Species

D. melanogaster

Name

FlyBase ID

FBal0400174

Feature type

allele

Associated gene

Dmel\Rer1

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Paul et al., 2024)

Progenitor genotype

P{SUPor-P}Rer1^KG08816

(Paul et al., 2024)

Cytology

Description

Imprecise excision of P{SUPor-P}Rer1^KG08816, resulting in a 1560bp deletion that covers the whole coding sequence of the Rer1 gene.

(Paul et al., 2024)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

cell lethal | larval stage | somatic clone

(Paul et al., 2024)

decreased size | larval stage | somatic clone

(Paul et al., 2024)

increased cell death | larval stage | somatic clone

(Paul et al., 2024)

lethal - all die before end of larval stage

(Paul et al., 2024)

Phenotype Manifest In

wing disc | somatic clone

(Paul et al., 2024)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Rer1^KO has increased cell death | larval stage | somatic clone phenotype, non-enhanceable by Gcn2^HMC06316/Scer\GAL4^αTub84B.PL

(Paul et al., 2024)

Rer1^KO has increased cell death | larval stage | somatic clone phenotype, non-enhanceable by bsk^DN.UAS/Scer\GAL4^αTub84B.PL

(Paul et al., 2024)

Rer1^KO has decreased size | larval stage | somatic clone phenotype, non-enhanceable by Myc^UAS.cZa/Scer\GAL4^αTub84B.PL

(Paul et al., 2024)

Suppressed by

Statement

Reference

Rer1^KO has decreased size | somatic clone | larval stage phenotype, suppressible by bsk^DN.UAS/Scer\GAL4^αTub84B.PL

(Paul et al., 2024)

Rer1^KO has decreased size | somatic clone | larval stage phenotype, suppressible by PEK^HMJ02063/Scer\GAL4^αTub84B.PL

(Paul et al., 2024)

Rer1^KO has increased cell death | somatic clone | larval stage phenotype, suppressible by PEK^HMJ02063/Scer\GAL4^αTub84B.PL

(Paul et al., 2024)

Rer1^KO has decreased size | somatic clone | larval stage phenotype, suppressible by PPP1R15^UAS.cMa/Scer\GAL4^αTub84B.PL

(Paul et al., 2024)

Rer1^KO has increased cell death | somatic clone | larval stage phenotype, suppressible by PPP1R15^UAS.cMa/Scer\GAL4^αTub84B.PL

(Paul et al., 2024)

NOT suppressed by

Statement

Reference

Rer1^KO has decreased size | somatic clone | larval stage phenotype, non-suppressible by Gcn2^HMC06316/Scer\GAL4^αTub84B.PL

(Paul et al., 2024)

Rer1^KO has increased cell death | somatic clone | larval stage phenotype, non-suppressible by Gcn2^HMC06316/Scer\GAL4^αTub84B.PL

(Paul et al., 2024)

Rer1^KO has increased cell death | somatic clone | larval stage phenotype, non-suppressible by bsk^DN.UAS/Scer\GAL4^αTub84B.PL

(Paul et al., 2024)

Rer1^KO has decreased size | somatic clone | larval stage phenotype, non-suppressible by Myc^UAS.cZa/Scer\GAL4^αTub84B.PL

(Paul et al., 2024)

Suppressor of

Statement

Reference

Rer1^KO is a suppressor | partially of increased size | somatic clone | larval stage phenotype of Myc^UAS.cZa, Scer\GAL4^Act5C.PP

(Paul et al., 2024)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Rer1^KO has wing disc | somatic clone phenotype, non-enhanceable by Gcn2^HMC06316/Scer\GAL4^αTub84B.PL

(Paul et al., 2024)

Rer1^KO has wing disc | somatic clone phenotype, non-enhanceable by Myc^UAS.cZa/Scer\GAL4^αTub84B.PL

(Paul et al., 2024)

Suppressed by

Statement

Reference

Rer1^KO has wing disc | somatic clone phenotype, suppressible by PEK^HMJ02063/Scer\GAL4^αTub84B.PL

(Paul et al., 2024)

Rer1^KO has wing disc | somatic clone phenotype, suppressible by PPP1R15^UAS.cMa/Scer\GAL4^αTub84B.PL

(Paul et al., 2024)

NOT suppressed by

Statement

Reference

Rer1^KO has wing disc | somatic clone phenotype, non-suppressible by Gcn2^HMC06316/Scer\GAL4^αTub84B.PL

(Paul et al., 2024)

Rer1^KO has wing disc | somatic clone phenotype, non-suppressible by Myc^UAS.cZa/Scer\GAL4^αTub84B.PL

(Paul et al., 2024)

Suppressor of

Statement

Reference

Rer1^KO is a suppressor | partially of wing disc | somatic clone phenotype of Myc^UAS.cZa, Scer\GAL4^Act5C.PP

(Paul et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Rer1^KO is rescued by Rer1^GFP

(Paul et al., 2024)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Rer1^KO

rer1^KO

(Paul et al., 2024)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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