FlyBase Allele Report: Dmel\side-VII[Δ3-4-1]

General Information

Symbol

Dmel\side-VII^Δ3-4-1

Species

D. melanogaster

Name

FlyBase ID

FBal0400434

Feature type

allele

Associated gene

Dmel\side-VII

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

CRISPR/Cas9

Nature of the Allele

Allele class

Mutagen

CRISPR/Cas9

(Osaka et al., 2024)

Progenitor genotype

Cytology

Description

Indel within side-VII. Sequence encoding the 3rd and 4th exons, and acceptor region of the 5th exon, is deleted.

(Osaka et al., 2024)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

delins

3R:9,738,081..9,738,767 [-]

Comment:

687bp deletion in side-VII. 18bp (GTAAGAGTAGTACTTACA) are inserted at the site of the deletion.

Inserted_sequence:

GTAAGAGTAGTACTTACA

(Osaka et al., 2024)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy

(Osaka et al., 2024)

abnormal neuroanatomy, with Scer\GAL4^GMR16H03, side-VII^KK109814

(Osaka et al., 2024)

abnormal neuroanatomy (with side-VII^Δ3-4-2)

(Osaka et al., 2024)

Phenotype Manifest In

lamina monopolar neuron

(Osaka et al., 2024)

lamina monopolar neuron, with Scer\GAL4^GMR16H03, side-VII^KK109814

(Osaka et al., 2024)

lamina monopolar neuron (with side-VII^Δ3-4-2)

(Osaka et al., 2024)

synapse, with Scer\GAL4^GMR16H03, side-VII^KK109814

(Osaka et al., 2024)

synapse | ectopic

(Osaka et al., 2024)

synapse | ectopic (with side-VII^Δ3-4-2)

(Osaka et al., 2024)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

side-VII^Δ3-4-1 has abnormal neuroanatomy phenotype, enhanceable by side-IV^Δ2/side-IV^Δ2

(Osaka et al., 2024)

Other

Statement

Reference

side-IV^Δ2, side-VII^Δ3-4-1 has abnormal neuroanatomy phenotype

(Osaka et al., 2024)

Phenotype Manifest In

Enhanced by

Statement

Reference

side-VII^Δ3-4-1 has synapse phenotype, enhanceable by side-IV^Δ2/side-IV^Δ2

(Osaka et al., 2024)

side-VII^Δ3-4-1 has lamina monopolar neuron phenotype, enhanceable by side-IV^Δ2/side-IV^Δ2

(Osaka et al., 2024)

Other

Statement

Reference

side-IV^Δ2, side-VII^Δ3-4-1 has synapse phenotype

(Osaka et al., 2024)

side-IV^Δ2, side-VII^Δ3-4-1 has lamina monopolar neuron L2 phenotype

(Osaka et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

side-VII^Δ3-4-1

(Osaka et al., 2024)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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