FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\osk2xSRE-
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General Information
Symbol
Dmel\osk2xSRE-
Species
D. melanogaster
Name
FlyBase ID
FBal0402032
Feature type
allele
Associated gene
Dmel\osk
Associated Insertion(s)
Carried in Construct
P{osk.2xSRE-}
Key Links
Transgenic product class
synonymous_variant
(Siddiqui et al., 2024)
Mutagen
Nature of the Allele
Transgenic product class
synonymous_variant
(Siddiqui et al., 2024)
Mutagen
in vitro construct
(Siddiqui et al., 2024)
Progenitor genotype
Carried in construct
P{osk.2xSRE-}
Cytology
Description

8kb genomic fragment that encompasses osk. The two smg-responsive elements (SREs), one in the coding sequence and one in the 3'UTR, have been mutated; the SRE sequence in the coding sequence has been mutated without altering the encoded amino acid sequence. The coding sequence is tagged at the C-terminal end with 6 His residues followed by 3xTag:HA.

(Siddiqui et al., 2024)
Allele components
Component
Use(s)
Encoded product / tool
osk
Tagged with
Tag:HA
Tag:polyHis
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      osk2xSRE- partially rescues osk0.RNA-null/Df(3R)osk

      (Siddiqui et al., 2024)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      osk2xSRE(-)
      (Siddiqui et al., 2024)
      osk2xSRE-
      Name Synonyms
      Secondary FlyBase IDs
        References (1)