FlyBase Allele Report: Dmel\Trabd[UAS.Tag:V5]

General Information

Symbol

Dmel\Trabd^UAS.Tag:V5

Species

D. melanogaster

Name

FlyBase ID

FBal0404535

Feature type

allele

Associated gene

Dmel\Trabd

Associated Insertion(s)

Carried in Construct

P{UAS-Trabd.V5}

Key Links

Transgenic product class

wild_type

(Zhou et al., 2024)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Zhou et al., 2024)

Mutagen

in vitro construct

(Zhou et al., 2024)

Progenitor genotype

Carried in construct

P{UAS-Trabd.V5}

Cytology

Description

UASt regulates expression of Trabd tagged with Tag:V5.

(Zhou et al., 2024)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Trabd

Tagged with

Tag:V5

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of neurodegenerative disease

CEA

(Zhou et al., 2024)

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

model of neurodegenerative disease

is exacerbated by Drp1^UAS.cDa

(Zhou et al., 2024)

exacerbates tauopathy

modeled by Hsap\MAPT^GMR.Ex.PJ

(Zhou et al., 2024)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased cell number | adult stage | progressive, with Scer\GAL4^GMR.PU

(Zhou et al., 2024)

decreased cell number | adult stage | progressive, with Scer\GAL4^ninaE.PU

(Zhou et al., 2024)

Phenotype Manifest In

adult muscle system, with Scer\GAL4^Mef2.PU

(Zhou et al., 2024)

embryonic/larval fat body | larval stage, with Scer\GAL4^Cg.PU

(Zhou et al., 2024)

eye photoreceptor cell | adult stage | decreased number, with Scer\GAL4^GMR.PU

(Zhou et al., 2024)

eye photoreceptor cell | adult stage | decreased number, with Scer\GAL4^ninaE.PU

(Zhou et al., 2024)

indirect flight muscle | adult stage, with Scer\GAL4^Mef2.PU

(Zhou et al., 2024)

mitochondrion | adult stage, with Scer\GAL4^Mef2.PU

(Zhou et al., 2024)

mitochondrion | larval stage, with Scer\GAL4^Cg.PU

(Zhou et al., 2024)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^GMR.PU, Trabd^UAS.Tag:V5 has decreased cell number | adult stage | progressive phenotype, enhanceable by Hsap\MAPT^GMR.Ex.PJ

(Zhou et al., 2024)

Scer\GAL4^GMR.PU, Trabd^UAS.Tag:V5 has decreased cell number | adult stage | progressive phenotype, enhanceable by Drp1^UAS.cDa, Scer\GAL4^GMR.PU

(Zhou et al., 2024)

Suppressed by

Statement

Reference

Drp1^UAS.cDa, Scer\GAL4^GMR.PU, Trabd^UAS.Tag:V5 has decreased cell number | adult stage | progressive phenotype, suppressible | partially by Hsap\MAPT^GMR.Ex.PJ

(Zhou et al., 2024)

Enhancer of

Statement

Reference

Trabd^UAS.Tag:V5/Scer\GAL4^GMR.PU is an enhancer of decreased cell number | adult stage | progressive phenotype of Hsap\MAPT^GMR.Ex.PJ

(Zhou et al., 2024)

Trabd^UAS.Tag:V5, Scer\GAL4^GMR.PU is an enhancer of decreased cell number | adult stage | progressive phenotype of Drp1^UAS.cDa, Scer\GAL4^GMR.PU

(Zhou et al., 2024)

Other

Statement

Reference

Hsap\MAPT^GMR.Ex.PJ, Scer\GAL4^GMR.PU, Trabd^UAS.Tag:V5 has visible | adult stage phenotype

(Zhou et al., 2024)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^GMR.PU, Trabd^UAS.Tag:V5 has eye photoreceptor cell | adult stage | decreased number phenotype, enhanceable by Hsap\MAPT^GMR.Ex.PJ

(Zhou et al., 2024)

Scer\GAL4^GMR.PU, Trabd^UAS.Tag:V5 has eye photoreceptor cell | adult stage | decreased number phenotype, enhanceable by Drp1^UAS.cDa, Scer\GAL4^GMR.PU

(Zhou et al., 2024)

Suppressed by

Statement

Reference

Drp1^UAS.cDa, Scer\GAL4^GMR.PU, Trabd^UAS.Tag:V5 has eye photoreceptor cell | adult stage | decreased number phenotype, suppressible | partially by Hsap\MAPT^GMR.Ex.PJ

(Zhou et al., 2024)

Enhancer of

Statement

Reference

Trabd^UAS.Tag:V5/Scer\GAL4^GMR.PU is an enhancer of eye photoreceptor cell | adult stage | decreased number phenotype of Hsap\MAPT^GMR.Ex.PJ

(Zhou et al., 2024)

Trabd^UAS.Tag:V5, Scer\GAL4^GMR.PU is an enhancer of eye photoreceptor cell | adult stage | decreased number phenotype of Drp1^UAS.cDa, Scer\GAL4^GMR.PU

(Zhou et al., 2024)

Other

Statement

Reference

Hsap\MAPT^GMR.Ex.PJ, Scer\GAL4^GMR.PU, Trabd^UAS.Tag:V5 has eye phenotype

(Zhou et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Trabd^UAS.Tag:V5

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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