FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\wall1
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General Information
Symbol
Dmel\wall1
Species
D. melanogaster
Name
FlyBase ID
FBal0406812
Feature type
allele
Associated gene
Dmel\wall
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Scanlan and Robin, 2024)
Mutagen
CRISPR/Cas9
(Scanlan and Robin, 2024)
Progenitor genotype
Cytology
Description

Comprises 2 deletions in the coding region of wall : a 381 bp in-frame deletion in exon 1 and a 2 bp frameshift deletion in exon 2. These lesions are predicted to significantly disrupt the function of the encoded protein, due to the deleted coding sequence (including the ATP-binding Brenner's motif) and frameshifts.

(Scanlan and Robin, 2024)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3L:20,232,112..20,232,491 [+]
Comment:

380bp deletion in wall. One of two deletions in mutant. Deletion mapped according to the junction sequences in Figure 2b. This disagrees with the text, which reports a 381bp in-frame deletion. One of two deletions in mutant.

(Scanlan and Robin, 2024)
deletion
3L:20,232,711..20,232,712 [+]
Comment:

2bp deletion in wall. One of two deletions in mutant.

(Scanlan and Robin, 2024)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      pkm2, wall1 has viable phenotype

      (Scanlan and Robin, 2024)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      wall1
      (Scanlan and Robin, 2024)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)