FB2026_02 , released June 18, 2026
Allele: Dmel\Epg5KO
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General Information
Symbol
Dmel\Epg5KO
Species
D. melanogaster
Name
FlyBase ID
FBal0407004
Feature type
allele
Associated gene
Dmel\Epg5
Associated Insertion(s)
TI{TI}Epg5KO
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Deneubourg et al., 2025)
Mutagen
CRISPR/Cas9
(Deneubourg et al., 2025)
gene targeting by homologous recombination
(Deneubourg et al., 2025)
Progenitor genotype
Associated Insertion(s)
TI{TI}Epg5KO
Cytology
Description

The Epg5 coding region is replaced by attP-loxP-mCherry-loxP.

(Deneubourg et al., 2025)
Allele components
Component
Use(s)
Tagged with
mCherry
Also carries
attP
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
3R:18,751,711..18,757,348 [-]
Comment:

The Epg5 coding region is replaced by attP-loxP-mCherry-loxP. Position of deletion endpoints on reference sequence determined from reported primer sequences used to generate homology arms.

(Deneubourg et al., 2025)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  Vici syndrome
      CEA
      (Deneubourg et al., 2025)
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      model of  Vici syndrome
      is ameliorated by Snap25JF02615
      (Deneubourg et al., 2025)
      ameliorates  epilepsy
      modeled by Snap25JF02615
      (Deneubourg et al., 2025)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Epg5KO
      epg5ko
      (Deneubourg et al., 2025)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)