FlyBase Allele Report: Dmel\Cdc73L[FS3]

FB2026_02 , released June 18, 2026

FB2026_02 , released June 18, 2026

Allele: Dmel\Cdc73L^FS3

General Information

Symbol

Dmel\Cdc73L^FS3

Species

D. melanogaster

Name

FlyBase ID

FBal0409887

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

loss of function allele

Mutagen

CRISPR/Cas9

Nature of the Allele

Allele class

loss of function allele

(Vilstrup et al., 2024)

Mutagen

(Vilstrup et al., 2024)

Progenitor genotype

Cytology

Description

CRISPR/Cas9 generated Cdc73L frameshift allele.

(Vilstrup et al., 2024)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female fertile (with Cdc73L^FS1)

(Vilstrup et al., 2024)

female fertile (with Cdc73L^FS2)

(Vilstrup et al., 2024)

male sterile (with Cdc73L^FS1)

(Vilstrup et al., 2024)

male sterile (with Cdc73L^FS2)

(Vilstrup et al., 2024)

viable (with Cdc73L^FS1)

(Vilstrup et al., 2024)

viable (with Cdc73L^FS2)

(Vilstrup et al., 2024)

Phenotype Manifest In

investment cone (with Cdc73L^FS1)

(Vilstrup et al., 2024)

Nebenkern (with Cdc73L^FS1)

(Vilstrup et al., 2024)

nucleus | spermatogenesis (with Cdc73L^FS1)

(Vilstrup et al., 2024)

spermatid (with Cdc73L^FS1)

(Vilstrup et al., 2024)

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Cdc73L^FS3

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections