FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Avic\GFPEGFP.UAS.Tag:MT(Khc)
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General Information
Symbol
Avic\GFPEGFP.UAS.Tag:MT(Khc)
Species
A. victoria
Name
FlyBase ID
FBal0410730
Feature type
allele
Associated gene
Avic\GFP
Associated Insertion(s)
Carried in Construct
P{UAS-MT(Khc)-EGFP}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Cook and Estes, 2006.12.4)
Progenitor genotype
Carried in construct
P{UAS-MT(Khc)-EGFP}
Cytology
Description

UASt regulatory sequences drive expression of EGFP fused to the Tag:MT(Khc) sequence (this contains the motor domain of Khc, targeting the tagged protein to the microtubule plus ends).

(Cook and Estes, 2006.12.4)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
EGFP
Tagged with
Tag:MT(Khc)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      exacerbates  Parkinson's disease
      modeled by Pink1B9
      (Liu et al., 2012)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Avic\GFPEGFP.UAS.Tag:MT(Khc)/Scer\GAL4Mhc.PU is an enhancer of wing phenotype of Pink1B9

      (Liu et al., 2012)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Khc248-2134.Scer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4Mhc.PU enhances the abnormal wing posture and flight defects of Pink1B9/Pink1B9 mutants.

      (Liu et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Avic\GFPEGFP.UAS.Tag:MT(Khc)
      Khc248-2134.Scer\UAS.T:Avic\GFP-EGFP
      Khc248-2134.UAS.EGFP
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0410684
      • FBal0193527
      References (6)