FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

adult Dh44 neuron of pars intercerebralis

ID (Ontology)

FBbt:00047127 (Fly Anatomy)

Definition

Diuretic hormone 44 (DH44)-expressing neuron of the adult having a cell body in the pars intercerebralis. There are three of these cells per hemisphere and they all coexpress leucokinin receptor (Cannell et al., 2016). These DH44 neurons synapse with Hugin neurons in the pars intercerebralis, the subesophageal zone and along the midline of the brain between these regions (King et al., 2017). Their subesophageal arborization is predominantly in the prow (Lee et al., 2015). It exits the brain via the nervus corporis cardiaci (McKim et al., 2024) and axons project to the foregut, anterior midgut and crop (Dus et al., 2015). It can be directly activated by the presence of nutritive sugars (Dus et al., 2015) or a small subset of amino acids (Yang et al., 2018) in the hemolymph.[ FlyBase:FBrf0152168 FlyBase:FBrf0227862 FlyBase:FBrf0228903 FlyBase:FBrf0232426 FlyBase:FBrf0236052 FlyBase:FBrf0240373 ]

Also Known As

"adult DH44 PI neuron" ; "adult DH44+ PI neuron" ; "adult m-NSC DH44"

Comment

Synapsing data shown by GRASP (King et al., 2017).

Links to External Ontologies

VFB:FBbt_00047127

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Insertions (FBti)	EXPRESSION_STAGE_TISSUE_POSITION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes	Insertions	Constructs
adult Dh44 neuron of pars intercerebralis (all annotations which use CV term, excluding "NOT" statements)

Spanning Tree (Parents/Children)

supraesophageal ganglion neuron
 |__adult neurosecretory cell of pars intercerebralis__
sensory neuron                                         |
 |__chemosensory neuron________________________________|
 |__adult sensory neuron_______________________________|
chemosensory system neuron                             |
 |__chemosensory neuron________________________________|
adult neuron                                           |
 |__adult gut-innervating neuron_______________________|
 |__adult sensory neuron_______________________________|
Dh44 neuron                                            |
 |__Dh44 neuron of pars intercerebralis________________|
 |__adult Dh44 neuron of brain_________________________|
neurosecretory cell of pars intercerebralis            |
 |__Dh44 neuron of pars intercerebralis________________|
 |__adult neurosecretory cell of pars intercerebralis__|
efferent neuron                                        |
 |__Dh44 neuron of pars intercerebralis________________|
adult efferent neuron                                  |
 |__adult ring gland projection neuron_________________|
gut-innervating neuron                                 |
 |__adult gut-innervating neuron_______________________|
neurosecretory cell of adult brain                     |
 |__adult neurosecretory cell of pars intercerebralis__|
 |__adult Dh44 neuron of brain_________________________|
adult peptidergic neuron                               |
 |__adult Dh44 neuron of brain_________________________|
                                                       adult Dh44 neuron of pars intercerebralis  14 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	chemosensory neuron Dh44 neuron of pars intercerebralis adult neurosecretory cell of pars intercerebralis adult Dh44 neuron of brain adult gut-innervating neuron adult sensory neuron adult ring gland projection neuron
Part of
Synonyms & Secondary IDs
Synonyms
	"adult DH44 PI neuron" EXACT "adult DH44+ PI neuron" EXACT[ FlyBase:FBrf0236052 ] "adult m-NSC DH44" EXACT
Secondary IDs

External Crossreferences & Linkouts
	VFB:FBbt_00047127