FB2026_03 , released September 17, 2026
CV Term Report
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Term adult doublesex aDN neuron ID (Ontology) FBbt:00047354 (Fly Anatomy)
Definition Doublesex-expressing neuron of the adult that has its soma in the anterodorsal region of the superior protocerebrum (Lee et al., 2002). There are two of these cells per hemisphere in both males and females (Nojima et al., 2021). In both sexes, their neurites are all ipsilateral, with a medial arbor in the superior medial protocerebrum containing mainly presynaptic sites (Nojima et al., 2021). Lateral arborization, containing mainly postsynaptic sites, is sexually-dimorphic (Nojima et al., 2021). These neurons are glutamatergic (Pavlou et al., 2016).[ FlyBase:FBrf0159058 FlyBase:FBrf0210397 FlyBase:FBrf0210735 FlyBase:FBrf0234085 FlyBase:FBrf0248430 ]
Also Known As"doublesex-expressing anterior-Dorsal Neuron" ; "dsx-aDN" ; "dsx-expressing anterior-Dorsal Neuron"
CommentLee et al. (2002) and Robinett et al. (2010) state that they do not see aDN in the female, but Rideout et al., 2010 and Pavlou et al., 2016 show that they are present in the female. These neurons do not express fruitless (Pavlou et al., 2016).
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VFB:FBbt_00047354
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Insertions (FBti)EXPRESSION_STAGE_TISSUE_POSITION
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 adult doublesex aDN neuron (all annotations which use CV term, excluding "NOT" statements)
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neuron
 |__sexually-dimorphic neuron________
adult neuron                         |
 |__adult glutamatergic neuron_______|
adult doublesex neuron               |
 |__adult brain doublesex neuron_____|
CNS neuron                           |
 |__supraesophageal ganglion neuron__|
adult CNS neuron                     |
 |__adult brain doublesex neuron_____|
glutamatergic neuron                 |
 |__adult glutamatergic neuron_______|
                                     adult doublesex aDN neuron  8 rec.
                                      |__adult doublesex aDN (female) neuron
                                      |__adult doublesex aDN (male) neuron
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Is a supraesophageal ganglion neuron
sexually-dimorphic neuron
adult brain doublesex neuron
adult glutamatergic neuron
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VFB:FBbt_00047354