Open Close
Reference
Citation
Pavlou, H.J., Lin, A.C., Neville, M.C., Nojima, T., Diao, F., Chen, B.E., White, B.H., Goodwin, S.F. (2016). Neural circuitry coordinating male copulation.  eLife 5(): e20713.
FlyBase ID
FBrf0234085
Publication Type
Research paper
Abstract

Copulation is the goal of the courtship process, crucial to reproductive success and evolutionary fitness. Identifying the circuitry underlying copulation is a necessary step towards understanding universal principles of circuit operation, and how circuit elements are recruited into the production of ordered action sequences. Here, we identify key sex-specific neurons that mediate copulation in Drosophila, and define a sexually dimorphic motor circuit in the male abdominal ganglion that mediates the action sequence of initiating and terminating copulation. This sexually dimorphic circuit composed of three neuronal classes - motor neurons, interneurons and mechanosensory neurons - controls the mechanics of copulation. By correlating the connectivity, function and activity of these neurons we have determined the logic for how this circuitry is coordinated to generate this male-specific behavior, and sets the stage for a circuit-level dissection of active sensing and modulation of copulatory behavior.

PubMed ID
PubMed Central ID
PMC5114013 (PMC) (EuropePMC)
Related Publication(s)
Note

The circuitry of sex.
Levine, 2016, eLife 5: e22215 [FBrf0239615]

Associated Information
Comments
Associated Files
Other Information
Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    eLife
    Title
    eLife
    ISBN/ISSN
    2050-084X
    Data From Reference