Gene Group: CLASS B GPCRs

General Information

Name

CLASS B GPCRs

Species

D. melanogaster

Symbol

GPCR-B

FlyBase ID

FBgg0000099

Date last reviewed

2023-06-30

Number of members

Description

Class B or secretin-like GPCRs have long N-terminal domains and form a group structurally and functionally divergent from other GPCR classes. Family B GPCRs can be divided into three subfamilies: B1, B2 and B3 (Methuselah-type). (Adapted from FBrf0221117).

Notes on Group

Source Material

The CLASS B GPCRs Gene Group has been compiled using the following publication(s): Vieira Contreras et al., 2024, Scholz et al., 2023, de Mendoza et al., 2016, Hanlon and Andrew, 2015, Araújo et al., 2013, Li et al., 2013, Vogel et al., 2013, Patel et al., 2012, Hauser et al., 2006, Hauser et al., 2006, Harmar, 2001, and Brody and Cravchik, 2000 .

Key Gene Ontology (GO) terms

Molecular Function

G protein-coupled receptor activity

Biological Process

G protein-coupled receptor signaling pathway

Cellular Component

plasma membrane

Related Gene Groups

Parent group(s)

G PROTEIN COUPLED RECEPTORS

Component group(s)

CLASS B GPCRs, SUBFAMILY B1