FB2026_03 , released September 17, 2026
Gene Group: SMOOTHENED-TYPE RECEPTORS
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General Information
Name
SMOOTHENED-TYPE RECEPTORS
Species
D. melanogaster
Symbol
SMO
FlyBase ID
FBgg0000135
Date last reviewed
2023-06-30
Number of members
1
Description
Description
smo is a Class F GPCR related to Frizzled GPCRs. It is a component of the hedgehog (hh) signaling pathway. smo is believed to signal via G protein independent and Gi-coupled pathways. (Adapted from FBrf0221081 and FBrf0201812).
Notes on Group

The SMO gene group has one member.

Source Material
The SMOOTHENED-TYPE RECEPTORS Gene Group has been compiled using the following publication(s): Hanlon and Andrew, 2015 and Brody and Cravchik, 2000 .
Key Gene Ontology (GO) terms
Molecular Function
transmembrane signaling receptor activity
Biological Process
smoothened signaling pathway
G protein-coupled receptor signaling pathway
Cellular Component
plasma membrane
Related Gene Groups
Parent group(s)
CLASS F GPCRs
Members (1)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
SMO
SMOOTHENED-TYPE RECEPTORS
Smoothened receptors
smo
Secondary FlyBase ID(s)
References (3)