Gene Group: CMGC KINASES

General Information

Name

CMGC KINASES

Species

D. melanogaster

Symbol

CMGC

FlyBase ID

FBgg0000226

Date last reviewed

2015-03-25

Number of members

Description

The CMGC family members are primarily proline-directed serine/threonine kinases. The CMGC family includes CDKs, GSKs, MAP kinases and CDK-like kinases. This large and well-conserved family of kinases have pivotal roles in cell cycle regulation and intracellular signal transduction. (Adapted from FBrf0132098).

Notes on Group

Source Material

The CMGC KINASES Gene Group has been compiled using the following publication(s): Chakrabarti et al., 2014, Sopko et al., 2014, Bartkowiak et al., 2010, Kinstrie et al., 2010, Manning et al., 2002, Allemand et al., 2001, Liu and Kipreos, 2000, and Morrison et al., 2000 .

Key Gene Ontology (GO) terms

Molecular Function

protein serine/threonine kinase activity

Biological Process

protein phosphorylation

Cellular Component

cytoplasm

Enzymatic activity

Enzyme name (EC)

non-specific serine/threonine protein kinase (2.7.11.1)

tropomyosin kinase (2.7.11.28)

[low-density-lipoprotein receptor] kinase (2.7.11.29)