Gene Group: PROTEIN KINASES

General Information

Name

PROTEIN KINASES

Species

D. melanogaster

Symbol

FlyBase ID

FBgg0000234

Date last reviewed

2015-03-25

Number of members

218

Description

Protein kinases are enzymes that covalently modify proteins by the addition of a phosphate group to serine, threonine and tyrosine residues typically using ATP as the phosphate donor. (Adapted from FBrf0132098).

Notes on Group

The grouping of protein kinase sub-families has been guided by the associated publications, Kinase.com and practical considerations. Groups contain catalytic subunits only. Known/putative pseudokinases are indicated in the Notes on Group section of the relevant subfamily report but are not included in the Members table - they are instead included in the PSEUDOKINASES gene group.

Source Material

The PROTEIN KINASES Gene Group has been compiled using the following publication(s): Mele and Johnson, 2019, Braden and Neufeld, 2016, Chakrabarti et al., 2014, Sopko et al., 2014, Vogel et al., 2013, Ishikawa et al., 2012, Bartkowiak et al., 2010, Kinstrie et al., 2010, Anamika et al., 2009, Delpire, 2009, Ishikawa et al., 2008, Chang et al., 2007, Mentzel and Raabe, 2005, Manning et al., 2002, Manning et al., 2002, Shieh et al., 2002, Allemand et al., 2001, Dan et al., 2001, Liu and Kipreos, 2000, Morrison et al., 2000, Han et al., 1998, and Campbell et al., 1995 .

Key Gene Ontology (GO) terms

Molecular Function

protein kinase activity

Biological Process

protein phosphorylation

Cellular Component

Related Gene Groups

Parent group(s)

KINASES

Component group(s)

AGC-KINASES

ATYPICAL PROTEIN KINASES