FB2026_02 , released June 18, 2026
Complex: TRANSCRIPTION FACTOR II D COMPLEX
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General Information
Name
TRANSCRIPTION FACTOR II D COMPLEX
Species
D. melanogaster
Symbol
TFIID
FlyBase ID
FBgg0000347
Date last reviewed
2026-04-13
Number of members
17
Description
Description
The general transcription factor complex Transcription factor II D (TFIID) plays an important role in recruiting the transcription machinery to core promoters. TFIID is a complex composed of TBP and several TBP-associated factors. (Adapted from FBrf0125116 and FBrf0156065).
Notes on Group

Hel89B is not included in the TRANSCRIPTION FACTOR II D gene group. The Hel89B helicase seems to play a gene-specific role in transcription regulation, rather than acting as a general transcription factor (FBrf0147041, FBrf0207888).

Source Material
The TRANSCRIPTION FACTOR II D COMPLEX Gene Group has been compiled using the following publication(s): Fan et al., 2017, Tora, 2002, Aoyagi and Wassarman, 2000, and Chen et al., 1994 .
Key Gene Ontology (GO) terms
Molecular Function
RNA polymerase II general transcription initiation factor activity
Biological Process
transcription initiation at RNA polymerase II promoter
Cellular Component
transcription factor TFIID complex
Related Gene Groups
Parent group(s)
GENERAL TRANSCRIPTION FACTOR COMPLEXES
Other related group(s)
TATA-BINDING PROTEIN AND TBP-RELATED FACTORS
TESTIS-SPECIFIC TBP-ASSOCIATED FACTORS
Members (17)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
TFIID
General transcription factor TFIID complex
TF-IID
TRANSCRIPTION FACTOR II D COMPLEX
TRANSCRIPTION FACTOR II D
Secondary FlyBase ID(s)
References (5)