FB2026_03 , released September 17, 2026
Complex: TRANSCRIPTION FACTOR II A COMPLEXES
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General Information
Name
TRANSCRIPTION FACTOR II A COMPLEXES
Species
D. melanogaster
Symbol
TFIIA
FlyBase ID
FBgg0000355
Date last reviewed
2026-04-13
Number of members
3
Description
Description
The general transcription factor complex Transcription factor II A (TFIIA) is not required for basal transcription but it stabilizes the TBP-DNA complex. TFIIA is RNA Pol II-specific and stimulates constitutive transcription and activated transcription. (Adapted from PMID:25693126).
Notes on Group

TfIIA-S-2 is a germline specific-isoform of TfIIA-S (FBrf0187387).

Source Material
The TRANSCRIPTION FACTOR II A COMPLEXES Gene Group has been compiled using the following publication(s): Aoyagi and Wassarman, 2000, Hansen and Tjian, 1995, and Yokomori et al., 1994 .
Key Gene Ontology (GO) terms
Molecular Function
RNA polymerase II general transcription initiation factor activity
Biological Process
transcription initiation at RNA polymerase II promoter
Cellular Component
transcription factor TFIIA complex
Related Gene Groups
Parent group(s)
GENERAL TRANSCRIPTION FACTOR COMPLEXES
Component group(s)
GENERAL TRANSCRIPTION FACTOR II A COMPLEX - GERMLINE SPECIFIC VARIANT
GENERAL TRANSCRIPTION FACTOR II A COMPLEX - TFIIA-S VARIANT
Members (3)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
TFIIA
General transcription factor TFIIA complex
TF-IIA
TRANSCRIPTION FACTOR II A COMPLEXES
TRANSCRIPTION FACTOR II A
Secondary FlyBase ID(s)
References (4)