FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene Group: HETEROTRIMERIC G-PROTEIN ALPHA SUBUNITS
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General Information
Name
HETEROTRIMERIC G-PROTEIN ALPHA SUBUNITS
Species
D. melanogaster
Symbol
G-SUB-A
FlyBase ID
FBgg0000463
Date last reviewed
2020-07-23
Number of members
8
Description
Description
The Heterotrimeric G-protein alpha subunits (Gα) can bind guanine nucleotide. When inactive, Gα is bound to GDP and associates with Gβγ forming an heterotrimer. Upon GTP binding, Gα dissociates from the heterotrimer Gαβγ. Gα has an intrinsic guanosine triphosphatase (GTPase) activity. (Adapted from FBrf0209904 and FBrf0183798).
Notes on Group
Source Material
The HETEROTRIMERIC G-PROTEIN ALPHA SUBUNITS Gene Group has been compiled using the following publication(s): Im et al., 2015, Krishnan et al., 2015, Boto et al., 2010, Katanayeva et al., 2010, and Colicelli, 2004 .
Key Gene Ontology (GO) terms
Molecular Function
GTPase activity
Biological Process
G protein-coupled receptor signaling pathway
Cellular Component
heterotrimeric G-protein complex
Related Gene Groups
Parent group(s)
GTPASES
HETEROTRIMERIC G-PROTEIN SUBUNITS
Members (8)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
Heterotrimeric-Gα
Gα
HETEROTRIMERIC G-PROTEIN ALPHA SUBUNITS
G-SUB-A
G-ALPHA-SUBUNIT
Secondary FlyBase ID(s)
References (6)