FB2026_02 , released June 18, 2026
Gene Group: SINE OCULIS HOMEOBOX TRANSCRIPTION FACTORS
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General Information
Name
SINE OCULIS HOMEOBOX TRANSCRIPTION FACTORS
Species
D. melanogaster
Symbol
SIX
FlyBase ID
FBgg0000751
Date last reviewed
2017-07-27
Number of members
3
Description
Description
Sine oculis homeobox (SIX) transcription factors are sequence-specific DNA binding proteins that regulate transcription and play important role in development. They are characterized by 120 amino acid SIX-type DNA-binding domain N-terminal to a homeodomain. (Adapted from FBrf0232555, FBrf0128773 and PMID:18797923).
Notes on Group
Source Material
The SINE OCULIS HOMEOBOX TRANSCRIPTION FACTORS Gene Group has been compiled using the following publication(s): Bürglin and Affolter, 2016, Zhong and Holland, 2010, and Kawakami et al., 2000 .
Key Gene Ontology (GO) terms
Molecular Function
DNA-binding transcription factor activity
transcription cis-regulatory region binding
Biological Process
regulation of DNA-templated transcription
Cellular Component
nucleus
Related Gene Groups
Parent group(s)
HOMEOBOX TRANSCRIPTION FACTORS
Members (3)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
SIX
SINE OCULIS HOMEOBOX TRANSCRIPTION FACTORS
SINE homeobox family
SINE
Secondary FlyBase ID(s)
References (4)