Gene Group: LIGASES

General Information

Name

LIGASES

Species

D. melanogaster

Symbol

LIG

FlyBase ID

FBgg0000801

Date last reviewed

2019-11-08

Number of members

128

Description

Ligases are enzymes that catalyze the joining of two molecules, or two groups within a single molecule, by forming a new chemical bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.

Notes on Group

Despite their common/historical name, the UBIQUITIN LIGASES (FBgg0000069) are correctly classified as 'transferases' rather than 'ligases', and so do not appear within the LIGASES gene group.

Source Material

The LIGASES Gene Group has been compiled using the following publication(s): François et al., 2023, Picchioni et al., 2019, Lu et al., 2015, Porcelli and Marygold, 2014.9.16, Du et al., 2011, Watkins et al., 2007, Caggese et al., 2006, Janke et al., 2005, Oba et al., 2005, Tripoli et al., 2005, and Pham and Sauer, 2000 .

Key Gene Ontology (GO) terms

Molecular Function

ligase activity

Biological Process

Cellular Component

Enzymatic activity

Enzyme name (EC)

6.-.-.-

Related Gene Groups

Parent group(s)

ENZYMES

Component group(s)