FB2026_03 , released September 17, 2026
Gene Group: CLASS II ALPHA-MANNOSIDASES
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General Information
Name
CLASS II ALPHA-MANNOSIDASES
Species
D. melanogaster
Symbol
GH38
FlyBase ID
FBgg0000833
Date last reviewed
2020-03-12
Number of members
8
Description
Description
Class II α-mannosidases (Glycoside hydrolase family 38) include Golgi enzymes involved in the removal of two different mannosyl linkages from GlcNAcMan(5)GlcNAc(2) to yield GlcNAcMan(3)GlcNAc(2), as well as lysosomal enzymes involved in the catabolism of glycoproteins. (Adapted from FBrf0223118).
Notes on Group
Source Material
The CLASS II ALPHA-MANNOSIDASES Gene Group has been compiled using the following publication(s): Rosenbaum et al., 2014, Lombard et al., 2013, and Nemčovičová et al., 2013 .
Key Gene Ontology (GO) terms
Molecular Function
alpha-mannosidase activity
Biological Process
N-glycan processing
Cellular Component
Enzymatic activity
Enzyme name (EC)
alpha-mannosidase (3.2.1.24)
Related Gene Groups
Parent group(s)
ALPHA-MANNOSIDASES
Component group(s)
GOLGI CLASS II ALPHA-MANNOSIDASES
LYSOSOMAL CLASS II ALPHA-MANNOSIDASES
Members (8)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
GH38
Glycoside hydrolase family 38
Class II α-mannosidases
CLASS II ALPHA-MANNOSIDASES
GH38 FAMILY OF CLASS II ALPHA-MANNOSIDASES
Secondary FlyBase ID(s)
References (4)