FB2026_03 , released September 17, 2026
Gene Group: FUMARATE HYDRATASES
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General Information
Name
FUMARATE HYDRATASES
Species
D. melanogaster
Symbol
FH
FlyBase ID
FBgg0000886
Date last reviewed
2023-09-12
Number of members
4
Description
Description
Fumarate hydratases are tricarboxylic-acid cycle enzymes that catalyze the reversible interconversion of fumarate and malate. (Adapted from FBrf0030365).
Notes on Group

Fum1, Fum2, Fum3 and Fum4 are paralogs: Fum1 is expressed ubiquitously, whereas Fum2, Fum3 and Fum4 are testis-specific.

Source Material
The FUMARATE HYDRATASES Gene Group has been compiled using the following publication(s): François et al., 2023 .
Key Gene Ontology (GO) terms
Molecular Function
fumarate hydratase activity
Biological Process
tricarboxylic acid cycle
Cellular Component
Enzymatic activity
Enzyme name (EC)
fumarate hydratase (4.2.1.2)
Related Gene Groups
Parent group(s)
HYDRO-LYASES
Members (4)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
FH
FUMARATE HYDRATASES
Fumarase
Secondary FlyBase ID(s)
References (3)