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General Information
Name
Hippo Signaling Pathway Core Components
Species
D. melanogaster
Symbol
SWH-C
FlyBase ID
FBgg0000913
Date last reviewed
2018-05-09
Number of members
6
Description
Description

The Hippo signaling pathway is an intracellular kinase cascade in which hpo kinase in complex with sav, phosphorylates wts kinase which, in turn, phosphorylates yki transcriptional co-activator leading to its cytosolic retention. Activation of the Hippo pathway results in the down-regulation of cell proliferation and up-regulation of apoptosis, limiting tissue size. (Adapted from FBrf0224870).

Notes and selected reviews
Biological Process Gene Ontology (GO) term(s)
Related Gene Groups
Physical Interaction Network
Members (6)
For all members:
External Data
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
SWH-C
Hippo Signaling Pathway Core Components
Hippo cascade
Secondary FlyBase ID(s)
References (34)