FB2026_03 , released September 17, 2026
Complex: CSL-NOTCH-MASTERMIND TRANSCRIPTION FACTOR COMPLEX
Open Close
General Information
Name
CSL-NOTCH-MASTERMIND TRANSCRIPTION FACTOR COMPLEX
Species
D. melanogaster
Symbol
CNM
FlyBase ID
FBgg0001066
Date last reviewed
2023-08-08
Number of members
3
Description
Description
The CSL-Notch-Mastermind transcription factor complex consisting of the CSL protein, Su(H), and mastermind (mam) protein, in complex with Notch intracellular domain (generated by ligand-stimulated N-cleavage), up-regulates transcription of Notch-responsive genes. (Adapted from FBrf0232880).
Notes on Group

CSL is an acronym of CBF1/RBP-J, Su(H), Lag-1, the mammalian, fly, and worm orthologous proteins, respectively (FBrf0232880).

Source Material
The CSL-NOTCH-MASTERMIND TRANSCRIPTION FACTOR COMPLEX Gene Group has been compiled using the following publication(s): Yuan et al., 2016, Contreras et al., 2015, and Maier et al., 2011 .
Key Gene Ontology (GO) terms
Molecular Function
DNA-binding transcription factor activity, RNA polymerase II-specific
Biological Process
positive regulation of transcription by RNA polymerase II
Notch signaling pathway
Cellular Component
CSL-Notch-Mastermind transcription factor complex
Related Gene Groups
Other related group(s)
NOTCH SIGNALING PATHWAY CORE COMPONENTS
Members (3)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
CNM
CSL-NOTCH-MASTERMIND TRANSCRIPTION FACTOR COMPLEX
CSL-NICD-MAM ternary complex
CSL-NICD-MAM
Secondary FlyBase ID(s)
References (4)